PVRL3

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PVRL3

Official Full Name poliovirus receptor-related 3
Background Nectins originally identified as poliovirus receptor-related protein (PRR) are Ca2+-independent immunoglobulin-like cell-cell-adhesion molecules. Nectins comprise a family of four members: nectin-1 (CD111/PRR1), nectin-2 (CD112/PRR2), nectin-3 (CD113/PRR3
Synonyms PVRL3; poliovirus receptor-related 3; poliovirus receptor-related protein 3; CD113; CDw113; DKFZP566B0846; nectin 3; PPR3; PVRR3; PRR3; NECTIN-3; FLJ90624
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian cells
    • Tag :
    • Avi
    • Fc
    • His
    • T7
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PVRL3-2186H Recombinant Human PVRL3 protein, His-tagged HEK293 His
    Human PVRL3-2187H Recombinant Human PVRL3 Protein, Fc-Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human PVRL3-2643HCL Recombinant Human PVRL3 cell lysate Human Cell N/A
    Human PVRL3-388H Recombinant Human PVRL3 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human PVRL3-692H Recombinant Human PVRL3 Protein, His-tagged Mammalian cells His
    Mouse PVRL3-13733M Recombinant Mouse Pvrl3 protein, His/T7-tagged E.coli His/T7

    PVRL3 involved in several pathways and played different roles in them. We selected most pathways PVRL3 participated on our site, such as Cell adhesion molecules (CAMs), Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PVRL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) BMA1; VTCN1; JAM2; BLB2; CADM1; CDH15; PTPRC; CLDN5; H2-AA; H2-Q10
    Adherens junction CDC42; MAP3K7; CSNK2A2A; IGF1RB; WASF1; WASL; WASLA; ACTN3; FGFR1A; CTNND1

    PVRL3 has several biochemical functions, for example, cell adhesion molecule binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PVRL3 itself. We selected most functions PVRL3 had, and list some proteins which have the same functions with PVRL3. You can find most of the proteins on our site.

    Function Related Protein
    cell adhesion molecule binding CDH1; ITGB3; PTBP3; CPE; ITGB2; MSN; CRTAM; TIGIT; CD1D; CADM1A
    protein binding OSBP; DYM; HIST1H4A; ERO1L; TWSG1; PIP5K1C; CDKN1A; Car8; PGR; KCNA1
    protein homodimerization activity STOM; VEGFA; BNIP3; LILRB1; VWF; SMAD3; GTF2A2; LGALS6; CARM1; CEP57
    receptor activity ANTXRL; GP6; PAQR3B; PAQR3A; NRXN1; DARC; RTN4RL2; ADIPOR2; RAMP3; CADM2A
    receptor binding TMED1; RND1; Icosl; CTNND1; MAG; SCYL2; SLC27A2; VTCN1; PAOX; FGF24

    PVRL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PVRL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PVRL3.

    MLLT4; PVRL2; PVRL1; RGS20; KRTAP10-7; KRTAP10-8

    Pang, J; Borjeson, TM; et al. Megaesophagus in a Line of Transgenic Rats: A Model of Achalasia. VETERINARY PATHOLOGY 51:1187-1200(2014).
    Lachke, SA; Higgins, AW; et al. The cell adhesion gene PVRL3 is associated with congenital ocular defects. HUMAN GENETICS 131:235-250(2012).

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