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Official Full Name ring finger protein 43
Synonyms RNF43;ring finger protein 43;18505;ENSG00000108375;URCC;RNF124;17q22;FLJ20315, FLJ77466, FLJ99338, MGC125630, DKFZp781H0392, DKFZp781H02126;E3 ubiquitin-protein ligase RNF43;E3 ubiquitin-protein ligase RNF43;
    • Species :
    • Human
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNF43-1145H Recombinant Human RNF43 Mammalian Cell His
    Human RNF43-767H Recombinant Human RNF43 Protein, Fc-tagged HEK293 Fc
    Human RNF43-768H Recombinant Human RNF43 Protein, His-tagged HEK293 His

    rnf43 involved in several pathways and played different roles in them. We selected most pathways rnf43 participated on our site, such as Disease, Diseases of signal transduction, RNF mutants show enhanced WNT signaling and proliferation, which may be useful for your reference. Also, other proteins which involved in the same pathway with rnf43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Diseases of signal transduction HEYL; JAG2; MIB1; CUX1; OPN1LW; TTR; OPN1MW; RBP4; CDK8; KREMEN1
    RNF mutants show enhanced WNT signaling and proliferation RNF43
    Regulation of FZD by ubiquitination RSPO1; LGR4; RNF43; ZNRF3; RSPO2; RSPO4; RSPO3; FMNL3; LGR6; LGR5
    Signal Transduction LINGO1; NEDD8L; GMIP; KAL1; RBP1; OR4D2; MDKA; ADH8B; OR2AP1; TAC2
    Signaling by WNT in cancer RNF43; KREMEN1; KREMEN2; TNKS; TNKS2
    Signaling by Wnt TNKS; RYK; ROR2; WLS; SOX9B; RSPO4; TMED5; KLHL12; WNT8-2; SOX9A
    TCF dependent signaling in response to WNT ASH2L; C; HECW1; HECW1B; SOX9B; WIF1; KLHL12; CDC73; WNT8-2; ZNRF3

    rnf43 has several biochemical functions, for example, frizzled binding, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by rnf43 itself. We selected most functions rnf43 had, and list some proteins which have the same functions with rnf43. You can find most of the proteins on our site.

    Function Related Protein
    frizzled binding WNT2B; SDCBP; WNT7B; WNT9B; FZD7; WNT8B; DVL3A; WNT2; WNT4A; WNT6
    ligase activity MKRN2; UBR2; RNF144AB; RFWD2; HLTF; UBE2I; RBBP6; PARK2; TRIM31; MKRN1
    protein binding CCDC50; MRPL11; ZFP488; TMEM174; SIX4; HDAC4; ATP7A; PSG1; RAB5C; DTX3
    ubiquitin-protein transferase activity TRIM68; UBR3; FBXO9; UBE2L3; TRIM28; HERC2; ZNF738; FBXO30A; SIAH2L; RNF220
    zinc ion binding PDLIM2; RNFT2; PPARAB; ZCCHC2; DPP3; ISL1; MORC4; RNF10; QPCTL; KDM5BA

    rnf43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rnf43 here. Most of them are supplied by our site. Hope this information will be useful for your research of rnf43.


    Sakamoto, H; Kuboki, Y; et al. Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas. MODERN PATHOLOGY 28:261-267(2015).
    Xi, SY; Zhang, XK; et al. Downregulation of ring-finger protein 43 in glioma associates with poor prognosis. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 8:490-496(2015).

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