rnps1 Protein, RNA binding protein S1, serine-rich domain

rnps1

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rnps1

Official Full Name RNA binding protein S1, serine-rich domain
Background This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Synonyms RNPS1; RNA binding protein S1, serine-rich domain; E5.1; RNA-binding protein with serine-rich domain 1; SR protein; SR-related protein LDC2; RNA-binding protein S1, serine-rich domain;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RNPS1-179H Recombinant Human RNPS1 protein, T7-tagged E.coli T7
    Human RNPS1-2258HCL Recombinant Human RNPS1 293 Cell Lysate HEK293 N/A
    Human RNPS1-2259HCL Recombinant Human RNPS1 293 Cell Lysate HEK293 N/A
    Human RNPS1-2354H Recombinant Human RNPS1, GST-tagged E.coli GST
    Mouse RNPS1-14365M Recombinant Mouse RNPS1 Protein Mammalian Cell His
    Rat RNPS1-5091R Recombinant Rat RNPS1 Protein Mammalian Cell His
    Zebrafish RNPS1-10150Z Recombinant Zebrafish RNPS1 Mammalian Cell His

    rnps1 involved in several pathways and played different roles in them. We selected most pathways rnps1 participated on our site, such as Cleavage of Growing Transcript in the Termination Region, Gene Expression, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC), which may be useful for your reference. Also, other proteins which involved in the same pathway with rnps1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cleavage of Growing Transcript in the Termination Region CLP1; LSM11; ZNF473; CSTF2; SRSF11; U2AF2; CSTF1; RNPS1; SLBP; CSTF3
    Gene Expression HNRPL; RRAGB; CBX3; PPARAA; CHD4A; ZNF264; RXRBB; ZNF706; NRBP1; GATAD2B
    Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) SMG9; RNPS1; SMG8
    Nonsense-Mediated Decay (NMD) SMG9; RNPS1; SMG8
    Processing of Capped Intron-Containing Pre-mRNA CCAR1; HNRNPH1; SRSF11; HNRNPD; DNAJC8; METTL3; PTBP1B; PRPF8; METTL14; SFRS3A
    RNA Polymerase II Transcription SLBP; CSTF1; GM3258; SSRP1A; RNPS1; CCNT2B; CSTF3; U2AF2; SUPT16H; PAPOLA
    RNA Polymerase II Transcription Termination CSTF3; CSTF2; THOC4; ZNF473; ZFP473; SLBP; PAPOLA; LSM11; NUDT21; CLP1
    RNA transport PABPC3; THOC4; EIF4BA; EIF1B; KPNB1; EIF4G2B; RAN; NUP205; NXT1; ALYREF

    rnps1 has several biochemical functions, for example, NOT RNA binding, mRNA 3-UTR binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by rnps1 itself. We selected most functions rnps1 had, and list some proteins which have the same functions with rnps1. You can find most of the proteins on our site.

    Function Related Protein
    NOT RNA binding RNPS1; NCBP2
    mRNA 3-UTR binding RNF40; TARDBP; PPP1R2P9; AUH; RNF20; CSDA; CPEB2; CPEB3; YBX2; ELAVL1
    nucleotide binding VSIG8B; PKZ; CSTF2T; KIAA0430; SMG1; Atp8a2; SNRNP70; LEMD3; TARDBPL; CELF5A
    poly(A) RNA binding DDX3X; C9orf114; DMGDH; EBI3; EIF2AK2; RPL23; HDGF; UTP23; MBNL1; DHX15
    protein binding PI4K2A; ZNF624; XIRP2; POLR1A; KCNIP2; RAPGEF6; WDR25; REL; ZCCHC17; FAM53C

    rnps1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with rnps1 here. Most of them are supplied by our site. Hope this information will be useful for your research of rnps1.

    SRPK1; UPF3B; SART3; YWHAG; THRAP3; SRPK2; U2AF1; SRSF1

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