Recombinant Human RNPS1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RNPS1-1105H
• Product Overview: RNPS1 MS Standard C13 and N15-labeled recombinant protein (NP_006702) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34 kDa
• AA Sequence: MDLSGVKKKSLLGVKENNKKSSTRA PSPTKRKDRSDEKSKDRSKDKGATK ESSEKDRGRDKTRKRRSASSGSSST RSRSSSTSSSGSSTSTGSSSGSSSS SASSRSGSSSTSRSSSSSSSSGSPS PSRRRHDNRRRSRSKSKPPKRDEKE RKRRSPSPKPTKVHIGRLTRNVTKD HIMEIFSTYGKIKMIDMPVERMHPH LSKGYAYVEFENPDEAEKALKHMDG GQIDGQEITATAVLAPWPRPPPRRF SPPRRMLPPPPMWRRSPPRMRRRSR SPRRRSPVRRRSRSPGRRRHRSRSS SNSSRTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RNPS1 RNA binding protein with serine rich domain 1 [ Homo sapiens (human) ]
• Official Symbol: RNPS1
• Synonyms: RNPS1; RNA binding protein S1, serine-rich domain; RNA binding protein S1, serine rich domain; RNA-binding protein with serine-rich domain 1; SR protein; SR-related protein LDC2; RNA-binding protein S1, serine-rich domain; E5.1; MGC117332
• Gene ID: 10921
• mRNA Refseq: NM_006711
• Protein Refseq: NP_006702
• MIM: 606447
• UniProt ID: Q15287