RPS6KA6
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Official Full Name
ribosomal protein S6 kinase, 90kDa, polypeptide 6
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Overview
This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010] -
Synonyms
RPS6KA6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; RSK4; PP90RSK4; ribosomal protein S6 kinase alpha-6; RSK-4; p90RSK6; p90-RSK 6; S6K-alpha 6; S6K-alpha-6; ribosomal S6 kinase 4; 90 kDa ribosomal protein S6 kinase 6;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Human
- Mouse
- E.coli
- HEK293T
- Insect (sf21)
- Insect Cell
- Insect Cells
- Sf21
- Sf9 Insect Cell
- GST
- His
- Myc
- DDK
- N/A
- N
- No tag
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
RPS6KA6 involved in several pathways and played different roles in them. We selected most pathways RPS6KA6 participated on our site, such as MAPK signaling pathway, Oocyte meiosis, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS6KA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | NTF4;IL1B;MAPKAPK3;CACNA1SA;FGF13;NGF;JUND;FGF10A;ARRB2B |
| Oocyte meiosis | SLKA;PPP1CC;YWHAB;MAP2K1;RPS6KA3;PTTG1;ESPL1;PLK1;YWHAG |
| mTOR signaling pathway | RPS6KB1B;CAB39;AKT1S1;IGF1;PRKCB;RPS6KA1;INS2;DEPDC6;PDPK1 |
| Long-term potentiation | PPP3CA;RPS6KA2;GRM5;PLCB2;RPS6KA6;PRKACG;PLCB4;KRAS;CAMK2G |
| Neurotrophin signaling pathway | ZFP110;NFKBIB;RAPGEF1;NGFR;TRAF6;PRKCD;CDC42;PLCG2;PRDM4 |
| Progesterone-mediated oocyte maturation | INS1;PIK3R3B;PIK3R1;MAPK1;RPS6KA1;PIK3CG;RPS6KA3;MAPK12A;PRKACAA |
| Insulin resistance | MAPK10;PRKAG1;RPS6KA1;PTENB;PPARA;PTPRF;RPS6KB2;STAT3;RPS6KA3A |
RPS6KA6 has several biochemical functions, for example, ATP binding, magnesium ion binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS6KA6 itself. We selected most functions RPS6KA6 had, and list some proteins which have the same functions with RPS6KA6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | EPHB6;CARKD;Abcb1b;MOV10B.2;ATAD2B;BUB1B;CMPK1;PRKCI;PANK1 |
| magnesium ion binding | OPA1;EYA2;NT5C1A;NLK;CERK;NLRC4;MAP3K5;ATP9A;ADSS |
| protein kinase activity | MAPK12A;BMPR1AA;ADRBK1;PAK2;FYNB;LTK;PRKD2;STK17B;PAK1 |
| ribosomal protein S6 kinase activity | RPS6KA4;RPS6KA3A;RPS6KA1;RPS6KB2;RPS6KB1B;RPS6KA2;RPS6KA6;RPS6KA3B;RPS6KB1 |
RPS6KA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS6KA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS6KA6.
HSP90AB1; DNAJC13; MED24; RPLP1; CLEC3B; CENPB; RXRA; NR4A1; DNMT1; MAPK3; MASP1; UFM1; LMO4; MPP1; CEBPZ; RBPJ; FZD5; DHX34; ADIRF; ZNF746
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