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RYR3

  • Official Full Name

    ryanodine receptor 3

  • Overview

    The protein encoded by this gene is a ryanodine receptor, which functions to release calcium from intracellular storage for use in many cellular processes. For example, the encoded protein is involved in skeletal muscle contraction by releasing calcium from the sarcoplasmic reticulum followed by depolarization of T-tubules. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    RYR3; ryanodine receptor 3; Brain ryanodine receptor calcium release channel; Brain ryanodine receptor-calcium release channel; Brain type ryanodine receptor; Brain-type ryanodine receptor; HBRR; RYR 3; RYR-3; RYR3_HUMAN;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RYR3-359H Recombinant Human RYR3 Mammalian Cell His
Human RYR3-790H Recombinant Human RYR3 Protein (3934-4181 aa), His-tagged E.coli His 3934-4181 aa
Human RYR3-4020H Recombinant Human RYR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human RYR3-4020H-B Recombinant Human RYR3 Protein Pre-coupled Magnetic Beads HEK293
Chicken RYR3-7089C Recombinant Chicken RYR3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RYR3 involved in several pathways and played different roles in them. We selected most pathways RYR3 participated on our site, such as Calcium signaling pathway, Circadian entrainment, Oxytocin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RYR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayORAI1;PRKACB;AVPR1B;ATP2A2;CCKBR;ORAI2;PRKACAB;ATP2A1;ATP2A2B
Circadian entrainmentGNG12;GNG2;PLCB2;CALML3;PRKCA;ADCYAP1R1;CAMK2D;PRKACB;GNAI2
Oxytocin signaling pathwayCACNA2D3;OXTR;CAMK4;RHOA;NPR1;PPP3CB;GUCY1A3;PIK3CG;NRAS
Salivary secretionCD38;DMBT1;CAP18;LYZ1;CAMP;CALM3;CST4;PRKACG;CALML3
Alzheimers diseaseNDUFC2;GRIN2B;NDUFA10;COX7A1;UQCRH;COX6A2;RYR3;PSEN1;LRP1

RYR3 has several biochemical functions, for example, calcium ion binding, calcium-induced calcium release activity, calcium-release channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RYR3 itself. We selected most functions RYR3 had, and list some proteins which have the same functions with RYR3. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPCDH15A;VIL1;PCDH1A3;CDH13;ARSA;PCDHA9;TLL1;CAPN3A;PLA2G12A
calcium-induced calcium release activityPKD2;RYR3;RYR2
calcium-release channel activityJPH3;RASA3;JPH2;RYR2;RYR3;RYR1;TRPV1
calmodulin bindingCNN1;DAPK1;CAMSAP1;MTAP6;CNN1A;ADCY3;CAMK1G;MKNK2;PLCB3
ryanodine-sensitive calcium-release channel activityRYR3;RYR2;RYR1B;RYR1

RYR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RYR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RYR3.

HNF1A; dcyD

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