sgcb

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sgcb

Official Full Name sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Background This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
Synonyms SGCB; sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); LGMD2E, sarcoglycan, beta (43kD dystrophin associated glycoprotein); beta-sarcoglycan; A3b; SGC; 43DAG; beta-SG; 43 kDa dystrophin-associated glycoprotein; limb girdle muscular dystrophy
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SGCB-1889HCL Recombinant Human SGCB 293 Cell Lysate HEK293 N/A
    Human SGCB-6512H Recombinant Human SGCB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human SGCB-75H Recombinant Human SGCB, His-tagged E.coli His
    Mouse SGCB-15029M Recombinant Mouse SGCB Protein Mammalian Cell His
    Mouse Sgcb-5821M Recombinant Mouse Sgcb Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Chicken SGCB-2826C Recombinant Chicken SGCB Mammalian Cell His
    Zebrafish SGCB-3448Z Recombinant Zebrafish SGCB Mammalian Cell His

    sgcb involved in several pathways and played different roles in them. We selected most pathways sgcb participated on our site, such as Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, which may be useful for your reference. Also, other proteins which involved in the same pathway with sgcb were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hypertrophic cardiomyopathy (HCM) TPM3; CACNB1; ITGAV; TGFB3; PRKAB2; MYL3; CACNB4; CACNG1; PRKAA1; ITGB7
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) ITGB7; CACNG2; CACNB3; ITGA7; ITGB1; ACTN1; LMNA; Itga10&Itgb1; ITGA10; ITGA3
    Dilated cardiomyopathy CACNG7; CACNG4; ITGA4; SLC8A1; ITGA5; ADRB1; CACNA2D4; ACTB; LMNA; CACNB1
    Viral myocarditis CD86; ITGB2; FYN; HLA-F; ABL2; EIF4G2; HLA-DRB3; HLA-DRB5; EIF4G3; HLA-DRA

    sgcb has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by sgcb itself. We selected most functions sgcb had, and list some proteins which have the same functions with sgcb. You can find most of the proteins on our site.

    Function Related Protein

    sgcb has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with sgcb here. Most of them are supplied by our site. Hope this information will be useful for your research of sgcb.

    TRIM63

    Stehlikova, K; Skalova, D; et al. Autosomal recessive limb-girdle muscular dystrophies in the Czech Republic. BMC NEUROLOGY 14:-(2014).
    Gibertini, S; Zanotti, S; et al. Fibrosis and inflammation are greater in muscles of beta-sarcoglycan-null mouse than mdx mouse. CELL AND TISSUE RESEARCH 356:427-443(2014).

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