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Official Full Name SH2 domain containing 1B
Background By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal;transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 (PubMed;11689425)).
Synonyms SH2D1B; SH2 domain containing 1B; SH2 domain-containing protein 1B; EAT2; EAT 2; EWS/FLI1 activated transcript 2; SH2 domain containing molecule EAT2; SH2 domain containing protein 1B; EAT-2; EWS/FLI1-activated transcript 2; SH2 domain-containing molecule EAT2
    • Species :
    • Chicken
    • Human
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SH2D1B-1337H Recombinant Human SH2D1B Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human SH2D1B-1597HCL Recombinant Human SH2D1B cell lysate N/A
    Human SH2D1B-210H Recombinant Human SH2D1B Protein, His-tagged Insect Cell His
    Human SH2D1B-2640H Recombinant Human SH2D1B, GST-tagged E.coli GST
    Chicken SH2D1B-5343C Recombinant Chicken SH2D1B Mammalian Cell His

    sh2d1b involved in several pathways and played different roles in them. We selected most pathways sh2d1b participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with sh2d1b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System KLRF1; CD200; AKR1C1; TREML1; RAET1E; CTSK; CLEC2D; TRIM69; SH2D1B; NRG4
    Immune System BST2; TRIM11; KLRB1A; KIF4A; TXNIP; HUWE1; TRIM10; GBP6; DEFA3; PLD4
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell SIGLEC6; LAIR2; SIGLEC12; TREML4; RAET1E; SIGLEC8; KLRB1F; CD200R1; LILRB5; LILRB1
    Natural killer cell mediated cytotoxicity PPP3CB; TNFRSF10D; KIR2DS3; RAET1L; SYK; FASLG; KIR2DS2; PIK3CG; KIR3DL2; PIK3CD

    sh2d1b has several biochemical functions, for example, protein binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by sh2d1b itself. We selected most functions sh2d1b had, and list some proteins which have the same functions with sh2d1b. You can find most of the proteins on our site.

    Function Related Protein
    protein binding FAM164C; BLOC1S4; LRPAP1; CHTOP; TRAPPC6A; GTF2A1L; IGFBP3; TOP2A; AGO2; LINGO1B
    protein binding, bridging FLRT3; MMS19; CSTA; VPS18; SYNM; CRADD; COL1A2; FBXW7; FLRT1; NEFL

    sh2d1b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with sh2d1b here. Most of them are supplied by our site. Hope this information will be useful for your research of sh2d1b.

    q53hf2_human; TRIM54; CD84; OLIG1; STAT4; ERBB2; MET

    Kurzer, JH; Argetsinger, LS; et al. Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta. MOLECULAR AND CELLULAR BIOLOGY 24:4557-4570(2004).

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