Recombinant Human SH2D1B Protein, His-tagged

• Cat.No.: SH2D1B-210H
• Product Overview: Recombinant Human SH2D1B(1-132aa) fused with His tag at C-terminal was expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 1-132aa
• Description: SH2D1B, also known as SH2 domain-containing protein 1B, is one of the proteins which activate NK cells. It plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells. Two isoforms of the human protein are produced by alternative splicing.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol.
• Molecular Mass: 16.4kDa (141aa) 18-28KDa (SDS-PAGE under reducing conditions.)
• AA Sequence: ADPMDLPYYH GRLTKQDCET LLLKEGVDGN FLLRDSESIP GVLCLCVSFK NIVYTYRIFR EKHGYYRIQT AEGSPKQVFP SLKELISKFE
  KPNQGMVVHL LKPIKRTSPS LRWRGLKLEL ETFVNSNSDY VDVLPHHHHH H
• Purity: > 90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: SH2D1B SH2 domain containing 1B [ Homo sapiens ]
• Official Symbol: SH2D1B
• Synonyms: SH2D1B; SH2 domain containing 1B; SH2 domain-containing protein 1B; EAT2; EAT-2; EWS/FLI1-activated transcript 2; SH2 domain-containing molecule EAT2
• Gene ID: 117157
• mRNA Refseq: NM_053282
• Protein Refseq: NP_444512
• MIM: 608510
• UniProt ID: O14796