SNX5 involved in several pathways and played different roles in them. We selected most pathways SNX5 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Endocytosis |
CHMP5; SH3GL3; PIP5KL1; SH3GLB2A; ARPC5; HLA-B; ZFYVE27; RHOA; HLA-G; TRAF6 |
SNX5 has several biochemical functions, for example, dynactin binding, phosphatidylinositol binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX5 itself. We selected most functions SNX5 had, and list some proteins which have the same functions with SNX5. You can find most of the proteins on our site.
| Function |
Related Protein |
| dynactin binding |
CCDC64; SNX6; BBS4; SNX5; PROL1; HTT; BICD1 |
| phosphatidylinositol binding |
TULP4; MTM1; ING2; SNX27B; ARHGAP32; SNX9A; FCHO2; ITPR3; SNX29; NOXO1 |
| protein binding |
RAB41; VEGFAB; EFNB2; RARRES2; KRTAP10-8; MLLT3; ATP1A1; RPS25; MYH7B; AP1M2 |
| protein heterodimerization activity |
SLC51B; HIST1H2AI; HIST1H2BN; TRP53; ODZ4; ABCG1; TAF13; DLG4B; HIST1H3G; EGFR |
SNX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX5.
APPBP2; SNX1; LAMTOR5; SNX2; PFDN1; PRKRA; HMOX2; MESDC2; ITSN1; ZYX; CDC37; pldB3; sspA; selA; q81kk8_bacan; MIB1; DNAJB11
Tan, XJ; Sun, Y; et al. LAPTM4B is a PtdIns(4,5)P-2 effector that regulates EGFR signaling, lysosomal sorting, and degradation. EMBO JOURNAL 34:475-490(2015).
Ghai, R; Tello-Lafoz, M; et al. Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells. JOURNAL OF CELL SCIENCE 128:553-565(2015).
