SNX9 Protein


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Official Full Name sorting nexin 9
Background This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation. [provided by RefSeq, Jul 2013]
Synonyms SNX9; sorting nexin 9; SDP1; WISP; SH3PX1; SH3PXD3A; sorting nexin-9; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; Wiskott-Aldrich syndrome protein (WASP) interactor protein;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Tag :
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SNX9-3536H Recombinant Human SNX9 protein, His-tagged E.coli His
    Human SNX9-1367H Recombinant Human SNX9 protein, His & T7-tagged E.coli His/T7
    Human SNX9-1584HCL Recombinant Human SNX9 293 Cell Lysate HEK293 N/A
    Mouse Snx9-6039M Recombinant Mouse Snx9 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    SNX9 involved in several pathways and played different roles in them. We selected most pathways SNX9 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNX9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Clathrin derived vesicle budding NAPAB; PICALM; CLTA; SNX9A; AP1G1; TBC1D8B; AP1M2; SNAPIN; SNX9B; AP1S3A
    Golgi Associated Vesicle Biogenesis FTH1A; PICALM; SNX9; SNX9A; HIP1R; CLINT1; AP1G1; TFR1B; SNX9B; PPIAL4A
    Membrane Trafficking TRAPPC6A; SNX9A; TPD52L1; TFG; SEC23IP; TRAPPC2; BET1; TRAPPC1; ARCN1; GORASP1
    Vesicle-mediated transport STXBP3; HIP1R; TPD52; TRAPPC6B; SNF8; PLDN; ARCN1B; CD163; CTAGE5; GJB3
    trans-Golgi Network Vesicle Budding CLVS1; GAK; PICALM; TPD52L1; DNASE2; CLVS2; YIPF6; FTH1B; SNAPIN; SNX9

    SNX9 has several biochemical functions, for example, 1-phosphatidylinositol binding, Arp2/3 complex binding, phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNX9 itself. We selected most functions SNX9 had, and list some proteins which have the same functions with SNX9. You can find most of the proteins on our site.

    Function Related Protein
    1-phosphatidylinositol binding SNX9; MCF2L; EEA1; ZFYVE9; ZFYVE16; SCARB1; SNX10; ZFYVE1; PICALMA; SYT1
    Arp2/3 complex binding SNX9; CORO1B; WHAMM; HAND2; GMFG; ARPC2; GMFB; PICK1
    phosphatidylinositol binding SNX33; SNX9; SLC12A9; SNX5; PIK3C2A; MITD1; SNX18A; SNX8; SH3YL1; SNX7
    protein binding PLAA; PACSIN2; PSKH1; KDM1A; IL13RA1; KCTD15; IFIH1; TSG101; TUBA3D; NOS3
    protein homodimerization activity SDCBP2; XPNPEP1; IKBKB; CDH13; UGT1A3; DMRTA2; ODZ4; UGT1A7; CADM1B; NFS1
    ubiquitin protein ligase binding CLU; PER1; HSPD1; ANAPC2; UBE2G1B; BLZF1; USP13; BID; RPA3; CUL2

    SNX9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNX9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNX9.

    DNM1; DNM2; ITCH; espF

    Tahoun, A; Siszler, G; et al. Comparative Analysis of EspF Variants in Inhibition of Escherichia coli Phagocytosis by Macrophages and Inhibition of E. coli Translocation through Human- and Bovine-Derived M Cells. INFECTION AND IMMUNITY 79:4716-4729(2011).
    Macaulay, SL; Stoichevska, V; et al. Insulin stimulates movement of sorting nexin 9 between cellular compartments: a putative role mediating cell surface receptor expression and insulin action. BIOCHEMICAL JOURNAL 376:123-134(2003).

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