|Official Full Name||sorting nexin 9|
|Background||This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation. [provided by RefSeq, Jul 2013]|
|Synonyms||SNX9; sorting nexin 9; SDP1; WISP; SH3PX1; SH3PXD3A; sorting nexin-9; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; Wiskott-Aldrich syndrome protein (WASP) interactor protein;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
snx9 involved in several pathways and played different roles in them. We selected most pathways snx9 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with snx9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Clathrin derived vesicle budding||FTH1A; SNX9B; CTSZ; DTNBP1B; FTH1B; PPIAL4A; BLOC1S1; TPD52L1; SNX9A; CNO|
|Golgi Associated Vesicle Biogenesis||AP1G1; PUM1; SNX9B; AP1S1; TPD52; DTNBP1; BLOC1S1; AP1S3A; AP1B1; SNAPIN|
|Membrane Trafficking||DAB2; SEC22C; ANKRD28; PPP6R1; COPE; GJB5; CNO; TRAPPC9; TFR1B; GJA4|
|Vesicle-mediated transport||SEC16B; TRAPPC6A; GAK; GJA5; SNX9B; GJA8; BLOC1S6; RALAA; LOC479668; CX30.3|
|trans-Golgi Network Vesicle Budding||FTH1B; HIP1RB; TCEAL4; BLOC1S6; CLINT1; DTNBP1; PICALM; SNX9B; SNX9A; AP3S1|
snx9 has several biochemical functions, for example, 1-phosphatidylinositol binding, Arp2/3 complex binding, phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by snx9 itself. We selected most functions snx9 had, and list some proteins which have the same functions with snx9. You can find most of the proteins on our site.
|1-phosphatidylinositol binding||SNX10; PICALMA; EPB41; SCIN; MCF2L; PLEKHA2; WDFY3; PLEKHA3; CCDC167; EEA1|
|Arp2/3 complex binding||ARPC2; HAND2; GMFG; GMFB; PICK1; CORO1B; SNX9; WHAMM|
|phosphatidylinositol binding||RPS6KC1; NOXO1A; HIP1RB; SNX25; ARHGAP32; ITPR1; SNX19A; SNX33; MYO1E; PIK3C2G|
|protein binding||RAB8B; ERLIN2; TRIM5; MERTK; KRT33B; NAA16; PELI3; CADM1; MLH3; KLHL18|
|protein homodimerization activity||CD200; NOG; G6PD; LDB1; CSF1; GABPB2; RNF40; NBL1; BHLHB9; Defa-rs7|
|ubiquitin protein ligase binding||SMAD2; USP13; AXIN1; EGR2; YOD1; CASC3; PA2G4; WASH; UBXN6; DLG3|
snx9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with snx9 here. Most of them are supplied by our site. Hope this information will be useful for your research of snx9.
DNM1; DNM2; ITCH; espF