Recombinant Full Length Human SNX9 Protein, C-Flag-tagged

• Cat.No.: SNX9-536HFL
• Product Overview: Recombinant Full Length Human SNX9 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N-terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non-receptor 2, Wiskott-Aldrich syndrome-like, and ARP3 actin-related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F-actin nucleation.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 66.4 kDa
• AA Sequence: MATKARVMYDFAAEPGNNELTVNEG EIITITNPDVGGGWLEGRNIKGERG LVPTDYVEILPSDGKDQFSC GNSVADQAFLDSLSASTAHASSSAA SNNHQVGSGNDPWSAWSASKSGNWE SSEGWGAQPEGAGAQRNTNT PNNWDTAFGHPQAYQGPATGDDDDW DEDWDGPKSSSYFKDSESADAGGAQ RGNSRASSSSMKIPLNKFPG FAKPGTEQYLLAKQLAKPKEKIPII VGDYGPMWVYPTSTFDCVVADPRKG SKMYGLKSYIEYQLTPTNTN RSVNHRYKHFDWLYERLLVKFGSAI PIPSLPDKQVTGRFEEEFIKMRMER LQAWMTRMCRHPVISESEVF QQFLNFRDEKEWKTGKRKAERDELA GVMIFSTMEPEAPDLDLVEIEQKCE AVGKFTKAMDDGVKELLTVG QEHWKRCTGPLPKEYQKIGKALQSL ATVFSSSGYQGETDLNDAITEAGKT YEEIASLVAEQPKKDLHFLM ECNHEYKGFLGCFPDIIGTHKGAIE KVKESDKLVATSKITLQDKQNMVKR VSIMSYALQAEMNHFHSNRI
  YDYNSVIRLYLEQQVQFYETIAEKL RQALSRFPVMSGPTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: SNX9 sorting nexin 9 [ Homo sapiens (human) ]
• Official Symbol: SNX9
• Synonyms: SDP1; WISP; SH3PX1; SH3PXD3A
• Gene ID: 51429
• mRNA Refseq: NM_016224.5
• Protein Refseq: NP_057308.1
• MIM: 605952
• UniProt ID: Q9Y5X1