SOX17

  • Official Full Name

    SRY (sex determining region Y)-box 17

  • Overview

    This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
  • Synonyms

    SOX17; SRY (sex determining region Y)-box 17; transcription factor SOX-17; SOX17_HUMAN; SRY (sex determining region Y) box 17; SRY box 17; SRY related HMG box transcription factor SOX17; Transcription factor SOX17; OTTHUMP00000226577; SRY-related HMG-box transcription factor SOX17; VUR3;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SOX17-1562HCL Recombinant Human SOX17 293 Cell Lysate HEK293 N/A
Human SOX17-2074H Recombinant Human SOX17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SOX17-301127H Recombinant Human SOX17 protein, GST-tagged E.coli GST Met1-Ser66
Human SOX17-3865H Recombinant Human SOX17 protein, His-tagged E.coli His 1-66 aa
Human SOX17-1911HFL Recombinant Full Length Human SOX17 Protein, C-Flag-tagged Mammalian cells Flag
Human SOX17-2074H-B Recombinant Human SOX17 Protein Pre-coupled Magnetic Beads HEK293
Human SOX17-3715H Recombinant Human SOX17 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse SOX17-15778M Recombinant Mouse SOX17 Protein Mammalian Cell His
Mouse Sox17-6052M Recombinant Mouse Sox17 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SOX17-8589M Recombinant Mouse SOX17 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SOX17-8589M-B Recombinant Mouse SOX17 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SOX17-8879Z Recombinant Zebrafish SOX17 Mammalian Cell His
Chicken SOX17-3381C Recombinant Chicken SOX17 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

SOX17 involved in several pathways and played different roles in them. We selected most pathways SOX17 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayWNT9B;NFATC3;WNT4;PRKACA;MMP7;WNT5A;RBX1;FBXW11A;BAMBIB

SOX17 has several biochemical functions, for example, beta-catenin binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX17 itself. We selected most functions SOX17 had, and list some proteins which have the same functions with SOX17. You can find most of the proteins on our site.

Function Related Protein
beta-catenin bindingCTNNBIP1;CTNNA1;TCF7L2;VCL;APC2;NUMB;DACT1;CXADR;LZTS2A
protein bindingGNG12;PCGF5;FKBP6;BIRC3;RAB1B;GRIN2C;XRN1;GPN3;DKC1
protein heterodimerization activityYWHAE;HER5;MCL1A;NEUROD1;IL12A;TP53;CHUK;HIST1H2BH;JDP2
sequence-specific DNA bindingLHX3;RX2;NR2C2;MAFBA;POU4F2;TFCP2L1;CXXC5;ERF;FOXC2
transcription coactivator activityLPIN1;TADA3;ACTL6B;NR1H3;ATF6;DDX5;MYOD1;NR1I2;YAP1
transcription factor activity, RNA polymerase II distal enhancer sequence-specific bindingPKNOX1;FOXF1;CEBPB;BHLHE40;PDX1;MYOG;RFX1;SFPI1;USF2
transcription factor bindingHES7;NEUROD1;THRA;HDAC9;ZEB1;GPX3;PARK7;AGTR2;MED25
transcription regulatory region DNA bindingSERPINB1A;POU5F1;PRDM5;TP73;SFPQ;GABPA;STAT3;SALL1A;KLF2A
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingHOXD8;RFX6;PKNOX1;ALX1;SOX17;RAD21;SOHLH1;EP300;FOXO3

SOX17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX17 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX17.

CTNNB1; EEFSEC; RPL38; Sox17; EBNA1BP2; HOMER3

Research Area

Related articles

Reers, S; Pfannerstill, AC; et al. Stem cell profiling in head and neck cancer reveals an Oct-4 expressing subpopulation with properties of chemoresistance. ORAL ONCOLOGY 50:155-162(2014).
Chieffi, P; Chieffi, S; et al. Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: An overview. JOURNAL OF CELLULAR PHYSIOLOGY 228:1641-1646(2013).
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