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Official Full Name Sp2 transcription factor
Background This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.
Synonyms SP2; Sp2 transcription factor; transcription factor Sp2; KIAA0048; OTTHUMP00000196580; SP2_HUMAN; SPECIFICITY PROTEIN 2
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SP2-1676HCL Recombinant Human SP2 cell lysate N/A
    Human SP2-31434TH Recombinant Human SP2 Wheat Germ N/A
    Human SP2-31435TH Recombinant Human SP2 Wheat Germ N/A
    Mouse SP2-15793M Recombinant Mouse SP2 Protein Mammalian Cell His
    Rhesus Macaque SP2-4418R Recombinant Rhesus monkey SP2 Protein, His-tagged Mammalian Cell His
    Zebrafish SP2-5794Z Recombinant Zebrafish SP2 Mammalian Cell His

    SP2 involved in several pathways and played different roles in them. We selected most pathways SP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    SP2 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding, histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SP2 itself. We selected most functions SP2 had, and list some proteins which have the same functions with SP2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding KCNA3; HIST1H47; INSM2; RBM5; HIST1H4I; ZNF12; ABI2; C14orf43; BRCA1; TCEA3
    RNA polymerase II transcription factor activity, sequence-specific DNA binding ZNF131; JUN; MAZ; FOXO1; RUNX2B; ELF2B; ZNF488; ETV2; FOXB1A; SOX14
    histone deacetylase binding CCND1; TRAF6; WDTC1; D7ERTD443E; NR2E1; NKX2-5; NR2C1; DNMT3B; XBP1; SFPQ
    metal ion binding TRIM35-31; ACSM2; PHF2; ITGA10; NCALDA; PC; TCN2; TEC; TRIM30A; ZFP513
    protein binding AATF; KCNJ5; VPS72; FCER2; INHA; HNRNPU; NCOR1; GAGE2D; PIFO; KAT2A

    SP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SP2.

    BANP; MCM7; FHL2

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