SPEG
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Official Full Name
SPEG complex locus
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Overview
This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies in mouse have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants have been reported for this gene, but the full-length nature of only two variants that encode different protein isoforms has been defined. -
Synonyms
SPEG; SPEG complex locus; aortic preferentially expressed gene 1 , APEG1; striated muscle preferentially expressed protein kinase; BPEG; KIAA1297; MGC12676; SPEGalpha; SPEGbeta; Aortic preferentially expressed gene 1; Aortic preferentially expressed protein 1; APEG 1; Nuclear protein marker for differentiated aortic smooth muscle and down regulated with vascular injury; nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury; APEG1; APEG-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
SPEG involved in several pathways and played different roles in them. We selected most pathways SPEG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SPEG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
SPEG has several biochemical functions, for example, ATP binding, protein binding, protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPEG itself. We selected most functions SPEG had, and list some proteins which have the same functions with SPEG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ATP1A1A.5;CSNK1A1;TAE1;CHEK2;ABCB3L1;MYH15;KDRL;SGK1;TARS |
| protein binding | NME1;SPSB4;SZL;NSL1;PPP4R1;CD6;EPN3;LEMD3;AIPL1 |
| protein serine/threonine kinase activity | PKN2;SRPK1B;AKT1;MYO3B;PRKCZ;PRKD1;CDC42BPA;MAPKAPK2;TTN |
SPEG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPEG here. Most of them are supplied by our site. Hope this information will be useful for your research of SPEG.
PRMT1; czc8004; linkable pd173955 analogue; bosutinib; imatinib; MYC
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, CTTN protein has been implicated in neurological disorders such as Alzheimer's disease, and its role in these conditions is also being investigated.
Yes, CTTN protein interacts with various signaling pathways involved in cancer progression, including those regulating cell migration and invasion.
Elevated CTTN protein expression has been associated with poor prognosis and shorter survival in some cancer types.
Yes, CTTN protein is involved in various cellular processes such as cell adhesion, migration, and cytoskeletal dynamics.
CTTN protein expression can be evaluated using immunohistochemistry on tumor tissue samples obtained from patients.
Customer Reviews (3)
Write a reviewThe Aldehyde Protein exhibits an exceptional level of quality that surpasses my experimental requirements.
One remarkable aspect of the SPEG Protein is the outstanding technical support provided by the manufacturer.
Its impeccable purity and consistency have consistently delivered accurate and robust results, enabling me to make significant strides in my research.
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