|Official Full Name||ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1|
|Background||Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29.|
|Synonyms||ST8SIA1; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; sialyltransferase 8 (alpha N acetylneuraminate: alpha 2,8 sialytransferase, GD3 synthase) A , SIAT8, SIAT8A; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; ST8Sia I; gangliosid|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
st8sia1 involved in several pathways and played different roles in them. We selected most pathways st8sia1 participated on our site, such as Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - ganglio series, which may be useful for your reference. Also, other proteins which involved in the same pathway with st8sia1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Glycosphingolipid biosynthesis - lacto and neolacto series||B3GNT1; B4GALT1; FUT9; GCNT2; ABO; FUT2; B3GNTL2; ST3GAL3; B3GALT5; FUT9A|
|Glycosphingolipid biosynthesis - globo series||B3GALNT1; ST8SIA1; ST3GAL2; NAGA; FUT1; FUT9; GBGT1; GBGT1L4; HEXB; GLA|
|Glycosphingolipid biosynthesis - ganglio series||ST6GALNAC3; ST8SIA5; GLB1; ST6GALNAC4; SLC33A1; ST3GAL1; ST3GAL5; ST8SIA1; HEXB; B4GALNT1|
|Metabolic pathways||HSD11B1; CEPT1B; MT-ATP6; PTGS2B; BCAT1; PRIM1; NOS1; FH; ACAA1; PNP6|
st8sia1 has several biochemical functions, for example, alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity, sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by st8sia1 itself. We selected most functions st8sia1 had, and list some proteins which have the same functions with st8sia1. You can find most of the proteins on our site.
|alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity||ST8SIA1; ST8SIA3; ST8SIA2; ST8SIA5|
|sialyltransferase activity||ST3GAL3A; ST6GALNAC5B; ST6GALNAC1; ST6GALNAC2; ST6GAL2A; ST3GAL5L; ST6GALNAC3; ST6GALNAC5; ST8SIA1; ST6GALNAC4|
st8sia1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with st8sia1 here. Most of them are supplied by our site. Hope this information will be useful for your research of st8sia1.