SUPT4H1
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Official Full Name
suppressor of Ty 4 homolog 1 (S. cerevisiae) -
Overview
Transcription elongation factor SPT4 is a protein that in humans is encoded by the SUPT4H1 gene. -
Synonyms
SUPT4H1;suppressor of Ty 4 homolog 1 (S. cerevisiae);suppressor of Ty (S.cerevisiae) 4 homolog 1 , SUPT4H;transcription elongation factor SPT4;SPT4H;DRB sensitivity-inducing factor 14 kDa subunit;DRB sensitivity-inducing factor small subunit;DSIF p14;DSIF small subunit;hSPT4;SPT4;SPT4H_HUMAN;SUPT4H `1;SUPT4H
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- Zebrafish
- Cynomolgus
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
SUPT4H1 involved in several pathways and played different roles in them. We selected most pathways SUPT4H1 participated on our site, such as Abortive elongation of HIV-1 transcript in the absence of Tat,Disease,Formation of HIV elongation complex in the absence of HIV Tat, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUPT4H1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Formation of HIV elongation complex in the absence of HIV Tat | TH1L,COBRA1,PSTPIP2,WHSC2,SUPT5H,SSRP1,CDK9,RDBP,CTDP1,ELL |
| Formation of the HIV-1 Early Elongation Complex | CTDP1,RDBP,TH1L,SUPT5H,COBRA1,WHSC2 |
| Formation of HIV-1 elongation complex containing HIV-1 Tat | SUPT5H,TCEA1,SSRP1,WHSC2,TCEB3,CTDP1,ELL,RDBP,COBRA1,TH1L |
| Formation of RNA Pol II elongation complex | CDK9,CTDP1,SUPT5H,RDBP,ELL,PSTPIP2,NELFE,SSRP1A,TCEB3,TCEA1 |
| Abortive elongation of HIV-1 transcript in the absence of Tat | COBRA1,WHSC2,CTDP1,RDBP,SUPT5H,TH1L |
| Disease | FDX1L,AP1M2,CCDC167,JAG1,PDCD6IP,AP2M1,OS9,OGN,MYO18A,FDXR |
| Gene Expression | TRIM33,SMARCA5,PIWIL4,ZNF558,GTF3C4,MED23,ZNF71,TET1,ADAR,ZFP36L1B |
| Formation of the Early Elongation Complex | GM3258,RDBP,SUPT5H,NELFE,TH1L,CTDP1,COBRA1,WHSC2 |
Protein Function
SUPT4H1 has several biochemical functions, for example, protein binding,protein heterodimerization activity,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUPT4H1 itself. We selected most functions SUPT4H1 had, and list some proteins which have the same functions with SUPT4H1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FMO4,TF,TP63,CTNNB2,AHNAK2,CDKN1C,UNC119B,BBS5,AP2S1,CREM |
| zinc ion binding | PDLIM1,ZFR,BRF1B,CALR,ZCCHC6,ZRANB1B,TIMM10,SP140,TRAF4,TRIM45 |
| protein heterodimerization activity | SIM2,CLCN3,H2AFJ,HER1,CEBPE,PPP2R1A,ENO3,PRSS28,TP53,NEFH |
| transcription factor activity, sequence-specific DNA binding | TEAD3,SOX3,EF1,GATA3,DLX4,FBXW7,NR4A2B,DLX2,ZFY2,ZNF8 |
Interacting Protein
SUPT4H1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUPT4H1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUPT4H1.
SUPT5H;PDLIM1;ANXA5;LRIF1;NSG2;ssdna_dtdc;Smad6;Rprd1b
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