t

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t

Official Full Name T, brachyury homolog (mouse)
Background The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Synonyms T; T, brachyury homolog (mouse); TFT; SAVA; brachyury protein; protein T; T brachyury homolog;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Mouse
    • Rat
    • Wheat Germ
    • Tag :
    • hIgG/His
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TNFRSF25-10H Recombinant Human TNFRSF25 Protein, hIgG/His-tagged Insect Cell hIgG/His
    Human DMAB32033 Mouse Anti-TRIM27 Monoclonal Antibody Mouse N/A
    Human T-1294HCL Recombinant Human T 293 Cell Lysate HEK293 N/A
    Human T-130H Recombinant Human T Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human T-27668TH Recombinant Human T Wheat Germ N/A
    Human T-27672TH Recombinant Human T Wheat Germ N/A
    Mouse DMAB36386 Rat Anti-Timd2 Monoclonal Antibody Rat N/A
    Mouse DMAB36387 Rat Anti-Timd2 Monoclonal Antibody Rat N/A
    Mouse T-16350M Recombinant Mouse T Protein Mammalian Cell His
    Mouse T-6267M Recombinant Mouse T Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Chicken T-6500C Recombinant Chicken T Mammalian Cell His

    t involved in several pathways and played different roles in them. We selected most pathways t participated on our site, such as Cardiac Progenitor Differentiation, Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with t were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cardiac Progenitor Differentiation BMP1; TBX20; T; SIRPA; NKX2; IRX4; ROR2; LIN28A; LIN28B; ZFP42
    Regulation of Wnt-mediated beta catenin signaling and target gene transcription KRT1; HBP1; KCNIP4; CYR61; ZCCHC12; TCF4; SALL4; TLE2; BCL9; T

    t has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by t itself. We selected most functions t had, and list some proteins which have the same functions with t. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II activating transcription factor binding IFI27; ATF2; TBX6; RB1; ISL1; HEY2; BHLHE40; LDB1; TBX20; SIN3A
    RNA polymerase II core promoter proximal region sequence-specific DNA binding IRF1; ZNF664; DPF2; RELA; SOX10; EBF2; PGR; MESP1; KCNIP3; JUND
    RNA polymerase II distal enhancer sequence-specific DNA binding BACH1; NR1H4; PBX3; SFPI1; ATF2; REL; POU4F1; FLI1; RELA; JUN
    RNA polymerase II transcription factor binding GATA1A; TAL1; MIXL1; ZFPM1; NFATC1; ZFPM2; GFI1B; HCLS1; GATA5; SPI1
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding RFX1; OLIG2; FOXC1; PAX3; LEF1; GATA6; MYOG; NR1H4; MITF; NR5A1
    transcription factor activity, sequence-specific DNA binding CRX; FOXN4; TEAD3B; EF1; HOXA5; TRPS1; MEF2A; FOXG1C; HLFA; HOXA3A
    transcriptional repressor activity, RNA polymerase II transcription factor binding AHRRA; RIMKLB; TBX6; BHLHE40; PITX2; MINA; ELP2; T; CREBBP; AHRRB

    t has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with t here. Most of them are supplied by our site. Hope this information will be useful for your research of t.

    Yang, YR; Feng, JD; et al. Immune Responses to a Recombinant Rv0057-Rv1352 Fusion Protein of Mycobacterium tuberculosis. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:39-48(2015).
    Law, JKY; Susloparova, A; et al. Human T cells monitored by impedance spectrometry using field-effect transistor arrays: A novel tool for single-cell adhesion and migration studies. BIOSENSORS & BIOELECTRONICS 67:170-176(2015).

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