T
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Official Full Name
T, brachyury homolog (mouse) -
Overview
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012] -
Synonyms
T;T, brachyury homolog (mouse);TFT;SAVA;brachyury protein;protein T;T brachyury homolog
Recombinant Proteins
- Mouse
- Human
- Chicken
- Enterobacteria phage T4
- Bacteriophage K3
- Mammalian Cells
- Wheat Germ
- HEK293
- Mouse
- Rat
- E.coli
- In Vitro Cell Free System
- Insect Cells
- His
- Non
- DDK
- Myc
- Avi
- Fc
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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T-16350M | Recombinant Mouse T Protein | Mammalian Cells | Mouse | His |
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T-27668TH | Recombinant Human T | Wheat Germ | Human | Non | 377 amino acids |
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T-27672TH | Recombinant Human T | Wheat Germ | Human | Non | 99 amino acids |
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T-6500C | Recombinant Chicken T | Mammalian Cells | Chicken | His |
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T-1294HCL | Recombinant Human T 293 Cell Lysate | HEK293 | Human | Non |
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DMAB32033 | Mouse Anti-TRIM27 Monoclonal Antibody | Mouse | Human | Non |
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DMAB36386 | Rat Anti-Timd2 Monoclonal Antibody | Rat | Mouse | Non |
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DMAB36387 | Rat Anti-Timd2 Monoclonal Antibody | Rat | Mouse | Non |
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RFL22746EF | Recombinant Full Length Enterobacteria Phage T4 Lysis Protein(T) Protein, His-Tagged | E.coli | Enterobacteria phage T4 | His | Full L. Full Length (1-218) |
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T-130H | Recombinant Human T Protein, MYC/DDK-tagged | HEK293 | Human | DDK&Myc |
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T-510HF | Recombinant Full Length Human T Protein | In Vitro Cell Free System | Human | Full L. 377 amino acids |
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T-6267M | Recombinant Mouse T Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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T-754B | Recombinant Bacteriophage K3 T protein, His&Myc-tagged | E.coli | Bacteriophage K3 | His&Myc | 50-218a.a. |
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T-8938M | Recombinant Mouse T Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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T-8938M-B | Recombinant Mouse T Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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TNFRSF25-10H | Active Recombinant Human TNFRSF25 Protein, hIgG/His-tagged | Insect Cells | Human | Fc&His | 417 |
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Involved Pathway
T involved in several pathways and played different roles in them. We selected most pathways T participated on our site, such as Cardiac Progenitor Differentiation,Regulation of Wnt-mediated beta catenin signaling and target gene transcription, which may be useful for your reference. Also, other proteins which involved in the same pathway with T were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Regulation of Wnt-mediated beta catenin signaling and target gene transcription | CBY1,CDX1,ZCCHC12,TLE1,KCNIP4,KRT1,CYR61,TCF4,TLE4,MYOG |
Cardiac Progenitor Differentiation | BMP1,NIPAL1,TBX5,IRX4,LIN28A,ZFP42,ROR2,SOX1,SIRPA,NKX2 |
Protein Function
T has several biochemical functions, for example, RNA polymerase II activating transcription factor binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by T itself. We selected most functions T had, and list some proteins which have the same functions with T. You can find most of the proteins on our site.
Function | Related Protein |
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RNA polymerase II transcription factor binding | ZGLP1,GATA4,TEAD3,SFPI1,CHST13,MEF2A,GATA6,ZFPM1,TAL1,GATA1A |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | FOXF2A,MEF2C,FOXC2,SOX10,ZFHX3,SFPI1,NKX2,NKX2-5,POU3F1,PKNOX1 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | ZNF100,ZSCAN21,SOX1,DPF2,SFPI1,ETV1,TCF3A,ARNT2,PPARA,TBX3 |
transcriptional repressor activity, RNA polymerase II transcription factor binding | AHRRA,EOMES,CREBBP,PITX2,RIMKLB,TBX6,MINA,ELP2,AHRRB,MLIP |
RNA polymerase II distal enhancer sequence-specific DNA binding | ARID3B,GATA2,HOXB5,ATF2,CREB1,ARX,SOX10,SFPI1,PBX3,MED12 |
RNA polymerase II activating transcription factor binding | NCOR1,PITX2,NEUROD1,SIN3A,IFI27,NHLH2,DUSP26,SMAD3,BEX1,EGR2 |
transcription factor activity, sequence-specific DNA binding | GRHL3,SP140,FOXA1,ZNF454,NTNG1,TBX21,ZNF45,NOTCH1,TGIF1,SIM1B |
Interacting Protein
T has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with T here. Most of them are supplied by our site. Hope this information will be useful for your research of T.
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References
- Yang, YR; Feng, JD; et al. Immune Responses to a Recombinant Rv0057-Rv1352 Fusion Protein of Mycobacterium tuberculosis. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:39-48(2015).
- Law, JKY; Susloparova, A; et al. Human T cells monitored by impedance spectrometry using field-effect transistor arrays: A novel tool for single-cell adhesion and migration studies. BIOSENSORS & BIOELECTRONICS 67:170-176(2015).