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TAF1C

Official Full Name

TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
Overview

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding;protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds;to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory;signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding;different isoforms have been identified.
Synonyms

TAF1C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, C, 110kD; TATA box-binding protein-associated factor RNA polymerase I subunit C; MGC:39976; SL1; TAFI;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TAF1C-30935TH	Recombinant Human TAF1C, His-tagged	E.coli	His	Inquiry
Human	TAF1C-1733HCL	Recombinant Human TAF1C cell lysate		Non	Inquiry
Mouse	TAF1C-16392M	Recombinant Mouse TAF1C Protein	Mammalian Cell	His	Inquiry
Mouse	TAF1C-8966M-B	Recombinant Mouse TAF1C Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	TAF1C-8966M	Recombinant Mouse TAF1C Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi	Inquiry
Rat	TAF1C-5915R	Recombinant Rat TAF1C Protein	Mammalian Cell	His	Inquiry
Rat	TAF1C-5574R	Recombinant Rat TAF1C Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi	Inquiry
Rat	TAF1C-5574R-B	Recombinant Rat TAF1C Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TAF1C involved in several pathways and played different roles in them. We selected most pathways TAF1C participated on our site, such as Epigenetic regulation of gene expression, Gene Expression, Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Epigenetic regulation of gene expression	SUDS3;DNMT3A;RBB4L;TAF1C;PHF19;SAP30BP;EFCAB11;H3F3D;DNMT3L
Gene Expression	RDBP;ZNF691;ZNF729;YBX1;EEF1A2;ZNF34;HNRNPH2;SRSF11;CD3EAP
Negative epigenetic regulation of rRNA expression	SIN3B;TAF1B;SAP30BP;TAF1D;DNMT3B;BAZ2A;SAP18;EFCAB11;SAP30L
NoRC negatively regulates rRNA expression	TAF1A;TAF1D;CD3EAP;SIN3B;TAF1B;SAP30BP;DNMT1;SAP30L;TAF1C
RNA Polymerase I Chain Elongation	TAF1B;EFCAB11;CBX3A;UBTF;TAF1A;CD3EAP;TAF1D;TAF1C;CBX3
RNA Polymerase I Promoter Clearance	UBTF;GATAD2AB;GATAD2A;RRN3;TAF1D;EFCAB11;MTA3;MBD3;CD3EAP
RNA Polymerase I Promoter Escape	EFCAB11;TAF1D;UBTF;TAF1A;RRN3;TAF1C;CD3EAP;TAF1B
RNA Polymerase I Transcription	MTA2;CBX3A;TAF1D;MTA1;MBD3A;MBD3;CD3EAP;RRN3;MBD3B

TAF1C has several biochemical functions, for example, RNA polymerase I CORE element sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1C itself. We selected most functions TAF1C had, and list some proteins which have the same functions with TAF1C. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase I CORE element sequence-specific DNA binding	RRN3;SMARCB1;SMARCA4;TAF1C;BAZ2A;TAF1B;EFCAB11;PIH1D1
protein binding	EXOSC2;Acr;CD70;GTF2IRD2;SCOC;MT1X;EXOC3;GHRHR;BCL2L15

TAF1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1C here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1C.

TBP; SET; TAF12; TAF1B; TAF1D; TTR; TK1; H2AFX; SMN1; UFD1L