| Official Full Name | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| Background | Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding;protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds;to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory;signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding;different isoforms have been identified. |
| Synonyms | TAF1C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, C, 110kD; TATA box-binding protein-associated factor RNA polymerase I subunit C; MGC:39976; SL1; TAFI |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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TAF1C involved in several pathways and played different roles in them. We selected most pathways TAF1C participated on our site, such as Epigenetic regulation of gene expression, Gene Expression, Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Epigenetic regulation of gene expression | SAP18; EFCAB11; TAF1C; RRP8; DNMT3A; RBB4L; AEBP2; MTF2; SAP30BP; SUDS3 |
| Gene Expression | EIF1AXA; DNAJC8; ZNF599; COX18; TSEN15; ZNF773; LSM10; ZNF311; Txn1; CHD4 |
| Negative epigenetic regulation of rRNA expression | SAP30; RRP8; CD3EAP; SAP130; SAP30L; TAF1B; TAF1D; TAF1A; BAZ2A; SAP30BP |
| NoRC negatively regulates rRNA expression | TAF1C; SAP30BP; TAF1D; CD3EAP; SIN3B; DNMT1; DNMT3B; TAF1B; SAP30L; EFCAB11 |
| RNA Polymerase I Chain Elongation | CBX3A; CD3EAP; TAF1A; EFCAB11; TAF1D; TAF1C; UBTF; CBX3; TAF1B |
| RNA Polymerase I Promoter Clearance | TAF1C; CHD4; EHMT2; EFCAB11; MTA2; CHD4A; GATAD2AB; TAF1A; GATAD2B; MBD3 |
| RNA Polymerase I Promoter Escape | UBTF; CD3EAP; RRN3; TAF1A; TAF1D; TAF1C; TAF1B; EFCAB11 |
| RNA Polymerase I Transcription | MTA1; GATAD2B; PTRF; TAF1C; RRN3; CHD4A; MTA3; CD3EAP; TAF1A; GATAD2A |
TAF1C has several biochemical functions, for example, RNA polymerase I CORE element sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1C itself. We selected most functions TAF1C had, and list some proteins which have the same functions with TAF1C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase I CORE element sequence-specific DNA binding | SMARCB1; EFCAB11; TAF1C; RRN3; PIH1D1; BAZ2A; SMARCA4; TAF1B |
| protein binding | GFM1; USP6; ITM2A; ZBTB32; NGFR; FASN; SERPINB1A; SFRP1; ING1; TOR1A |
TAF1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1C here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1C.
TBP; SET; TAF12; TAF1B; TAF1D; TTR; TK1; H2AFX; SMN1; UFD1L
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