Recombinant Human TAF1C cell lysate

• Cat.No.: TAF1C-1733HCL

Specification

• Description: Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa [ Homo sapiens ]
• Official Symbol: TAF1C
• Synonyms: TAF1C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, C, 110kD; TATA box-binding protein-associated factor RNA polymerase I subunit C; MGC:39976; SL1; TAFI95; TAFI110; SL1, 110kD subunit; TBP-associated factor 1C; transcription factor SL1; TATA box-binding protein-associated factor 1C; transcription initiation factor SL1/TIF-IB subunit C; RNA polymerase I-specific TBP-associated factor 110 kDa
• Gene ID: 9013
• mRNA Refseq: NM_001243156
• Protein Refseq: NP_001230085
• MIM: 604905
• UniProt ID: Q15572
• Chromosome Location: 16q24
• Pathway: Gene Expression, organism-specific biosystem; RNA Polymerase I Chain Elongation, organism-specific biosystem; RNA Polymerase I Promoter Clearance, organism-specific biosystem; RNA Polymerase I Promoter Escape, organism-specific biosystem; RNA Polymerase I Transcription, organism-specific biosystem; RNA Polymerase I Transcription Initiation, organism-specific biosystem; RNA Polymerase I Transcription Termination, organism-specific biosystem
• Function: DNA binding