Recombinant Human TAF1C, His-tagged TAF1C-30935TH

Recombinant Human TAF1C, His-tagged

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Cat.No. : TAF1C-30935TH Optional Service: Optional requirements on this protein
Product Overview : Recombinant fragment, corresponding to amino acids 247-742 of Human TAF1C Isoform 2 with N terminal His tag; Predicted MWt 55 kDa.
Description : Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 163 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : TGISLSPHLP GELAICSRSG AVCLWSPEDG LRQIYRDPET LVFRDSSSWR WADFTAHPRV LTVGDRTGVK MLDTQGPP GCGLLLFRLG AEASCQKGER VLLTQYLGHS SPKCLPPT LHLVCTQFSL YLVDERLPLV PMLKWNHGLP SPLLLARL LPPPRPSCVQ PLLLGGQGGQ LQLLHLAEGA SVPRLAGPPQ SLPSRIDSLP AFPLLEPKIQ WRLQERLKAP TIGLAAVV PPLPSAPTPG LVLFQLSAAG DVFYQQLRPQ VDSSLRRD AGPPGDTQPD CHAPTASWTS QDTAGCSQWL KALLKVPL APPVWTAPTF THRQMLGSTE LRREEEEGQR LGVLRKAM ARGQLLLQRD LGSLPAAEPP PAPESGLEDK LSERLGEAWA GRGAAWWERQ QGRTSEPGRQ TRRPKRRTQL SSSFSLSG HVDPSEDTSS PHSPEWPPAD ALPLPPTTPP SQELTPDA CAQGVPSEQR QMLRDYMAKL PPQRDTPGCA TTPP
Gene Name : TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa [ Homo sapiens ]
Official Symbol : TAF1C
Synonyms : TAF1C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, C, 110kD; TATA box-binding protein-associated factor RNA polymerase I subunit C; MGC:39976; SL1; TAFI
Gene ID : 9013
mRNA Refseq : NM_001243156
Protein Refseq : NP_001230085
MIM : 604905
Uniprot ID : Q15572
Chromosome Location : 16q24
Pathway : RNA Polymerase I Chain Elongation, organism-specific biosystem; RNA Polymerase I Promoter Clearance, organism-specific biosystem; RNA Polymerase I Promoter Escape, organism-specific biosystem; RNA Polymerase I Transcription, organism-specific biosystem; RNA Polymerase I Transcription Initiation, organism-specific biosystem;
Function : DNA binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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