tbx3

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tbx3

Official Full Name T-box 3
Background This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
Synonyms TBX3; T-box 3; ulnar mammary syndrome , UMS; T-box transcription factor TBX3; TBX3 ISO; XHL; T-box protein 3; bladder cancer related protein XHL; UMS; TBX3-ISO
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TBX3-4445H Recombinant Human TBX3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TBX3-4867H Recombinant Human TBX3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Tbx3-6322M Recombinant Mouse Tbx3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human TBX3-1199HCL Recombinant Human TBX3 293 Cell Lysate HEK293 N/A
    Human TBX3-1586H Recombinant Human TBX3 protein, His-tagged E.coli His
    Human TBX3-29459TH Recombinant Human TBX3 Wheat Germ N/A
    Human TBX3-3143H Recombinant Human TBX3, GST-tagged E.coli GST
    Mouse Tbx3-1587M Recombinant Mouse Tbx3 protein, His-tagged E.coli His
    Mouse TBX3-16532M Recombinant Mouse TBX3 Protein Mammalian Cell His
    Rat Tbx3-1588R Recombinant Rat Tbx3 protein, His-tagged E.coli His
    Rat TBX3-5975R Recombinant Rat TBX3 Protein Mammalian Cell His
    Chicken TBX3-4655C Recombinant Chicken TBX3 Mammalian Cell His

    tbx3 involved in several pathways and played different roles in them. We selected most pathways tbx3 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with tbx3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Signaling pathways regulating pluripotency of stem cells BMPR1B; PIK3R1; IGF1; BMI1; ACVR2B; WNT7B; WNT3; ESX1; SMAD5; FZD6

    tbx3 has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tbx3 itself. We selected most functions tbx3 had, and list some proteins which have the same functions with tbx3. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II activating transcription factor binding BEX1; SMAD3; TP53BP1; BHLHE40; HIPK2; MAD2L2; DUSP26; HNF4A; NHLH2; JUN
    RNA polymerase II core promoter proximal region sequence-specific DNA binding MAFA; FOS; RFX5; NFATC3; SREBF1; TXK; CARF; RBPJ; RELA; ZFP746
    RNA polymerase II transcription factor binding ZFPM2A; CHST13; TAL1; Ar; WWP2; XBP1; ATF4; TP53; GATA3; GATA2
    protein binding SMARCA4; SNRPG; C9orf116; MOS; SMNDC1; HEMGN; Anks6; BBS1; TKT; BTN2A2
    sequence-specific DNA binding NFE2; ZBTB33; FOXB1; SHOX; VENT; HOXC5; UNCX4.1; HOXC4A; SIX4; BCL11AB
    transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding CC2D1B; PITX2; TBX3; CUX2; SFPI1; MXD1; POU4F2; OVOL1; IFI203; NR1D1

    tbx3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tbx3 here. Most of them are supplied by our site. Hope this information will be useful for your research of tbx3.

    CA8; AES; Dlg4; TOLLIP

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