TFDP1
-
Official Full Name
transcription factor Dp-1 -
Overview
This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X. -
Synonyms
TFDP1;transcription factor Dp-1;Dp 1;DP1;DRTF1;DRTF1-polypeptide 1;E2F dimerization partner 1;E2F-related transcription factor;Dp-1
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Flag
- Avi
- Fc
- DDK
- Myc
Involved Pathway
TFDP1 involved in several pathways and played different roles in them. We selected most pathways TFDP1 participated on our site, such as Cell cycle,TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFDP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | PLK4,YWHABL,SMC3,THRSP,HDAC2,NUDC,GADD45AB,VRK2,CCND3,RBBP8 |
| TGF-beta signaling pathway | TGFB1,TGFBR1A,SMAD2,BMP8B,BMP2B,ACVR1L,ID1,BMP2,TGIF2,LTBP1 |
Protein Function
TFDP1 has several biochemical functions, for example, DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFDP1 itself. We selected most functions TFDP1 had, and list some proteins which have the same functions with TFDP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein domain specific binding | HOMER2,BHLHE40,FOXA3,UNC13A,EHD2,HIST1H4K,YWHABB,FOXA1,HOMER3,Akap2 |
| transcription factor binding | PBX2,ETS1,DIP2A,TFDP1A,TFAP2A,KAT2B,LMO4,STK36,GATA2,APBB2 |
| transcription factor activity, sequence-specific DNA binding | ZNF583,SOX11,GATA2B,GTF2IRD1,EFCAB11,CEBP1,RARGA,DBPA,ZNF189,NFE2 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | TWIST1,ETV3,HIF1AL2,ZNF446,FLI1A,FLI1B,FOXO4,FOXD1L,NPAS4,TFDP2 |
| protein binding | CAMP,SHD,LYVE1,NUP62L,TEF,YWHAB,TMEM182,RABGAP1,USP17L2,PCMT1 |
| transcription coactivator activity | PPARGC1A,MED23,MED1,TADA2A,NFKBIB,USP16,JUNBA,KLF7,NFKB2,YAP1 |
| DNA binding | NR2F6,TSG101,FOXM1,FLYWCH1,ZFP276,LMX1BA,TCEA1,FOXC1,HES7,ZNF572 |
Interacting Protein
TFDP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFDP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TFDP1.
E2F1;E2F6;DVL1;RBL2
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