Recombinant Full Length Human TFDP1 Protein, C-Flag-tagged

• Cat.No.: TFDP1-1071HFL
• Product Overview: Recombinant Full Length Human TFDP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 44.9 kDa
• AA Sequence: MAKDAGLIEANGELKVFIDQNLSPG KGVVSLVAVHPSTVNPLGKQLLPKT FGQSNVNIAQQVVIGTPQRP AASNTLVVGSPHTPSTHFASQNQPS DSSPWSAGKRNRKGEKNGKGLRHFS MKVCEKVQRKGTTSYNEVAD ELVAEFSAADNHILPNESAYDQKNI RRRVYDALNVLMAMNIISKEKKEIK WIGLPTNSAQECQNLEVERQ RRLERIKQKQSQLQELILQQIAFKN LVQRNRHAEQQASRPPPPNSVIHLP FIIVNTSKKTVIDCSISNDK FEYLFNFDNTFEIHDDIEVLKRMGM ACGLESGSCSAEDLKMARSLVPKAL EPYVTEMAQGTVGGVFITTA
  GSTSNGTRFSASDLTNGADGMLATS SNGSQYSGSRVETPVSYVGEDDEED DDFNENDEDDTRTRPLEQKLISEED LAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Cell cycle, TGF-beta signaling pathway

Gene Information

• Gene Name: TFDP1 transcription factor Dp-1 [ Homo sapiens (human) ]
• Official Symbol: TFDP1
• Synonyms: DP1; DILC; Dp-1; DRTF1
• Gene ID: 7027
• mRNA Refseq: NM_007111.5
• Protein Refseq: NP_009042.1
• MIM: 189902
• UniProt ID: Q14186