TFF1
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Official Full Name
trefoil factor 1
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Overview
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. -
Synonyms
TFF1; trefoil factor 1; BCEI, breast cancer, estrogen inducible sequence expressed in; D21S21; HP1.A; HPS2; pNR 2; pS2; protein pS2; polypeptide P1.A; gastrointestinal trefoil protein pS2; breast cancer estrogen-inducible protein; breast cancer estrogen-;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Yeast
- C
- hFc
- His
- Fc
- Avi
- GST
- T7
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
TFF1 involved in several pathways and played different roles in them. We selected most pathways TFF1 participated on our site, such as FOXA1 transcription factor network, Integrated Pancreatic Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| FOXA1 transcription factor network | DSCAM;NFIC;TFF1;CEBPB;FOXA1;CYP2C18;NR2F2;NFIA;NRIP1 |
| Integrated Pancreatic Cancer Pathway | TFF1;PPP1R13L;MYT1;FKBP3;AGA;LEFTY1;RB1CC1;WRN;GPRC5A |
TFF1 has several biochemical functions, for example, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFF1 itself. We selected most functions TFF1 had, and list some proteins which have the same functions with TFF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| growth factor activity | GDF5;JAG1;FGF12B;INHBA;FGF2;FGF7;BMP2;BMP8A;FGF10A |
| protein binding | GLA;MED9;PROM1;DDB2;ZSCAN21;PTK2;HELLS;ATP6V1B2;PTRH2 |
TFF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TFF1.
ZNF250; BTN3A1; BTNL8; CD300LD; FCRL4; SIGLEC8; XRCC3; FGFR2
Research Area
Related articles
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewTFF1 protein is highly recommended for scientific research applications, especially in ELISA assays and protein electron microscopy structure analysis.
Its versatility in various biological applications, coupled with its compatibility with diverse techniques, makes it a preferred reagent for researchers in the field.
Scientists who have employed TFF1 protein in their experiments have praised its outstanding performance and reliability.
Q&As (5)
Ask a questionYes, FGFR3-targeted therapies are being developed for cancer treatment, particularly for patients with FGFR3 mutations.
FGFR3 testing can aid in diagnosing specific types of cancer, especially bladder cancer, where FGFR3 mutations are prevalent.
FGFR3-targeted therapies may involve small molecule inhibitors or monoclonal antibodies that specifically block the activity of mutated FGFR3.
Mutations in the FGFR3 gene can lead to the development of certain cancers, including bladder cancer and multiple myeloma.
FGFR3 testing is becoming more common, especially in cases where specific cancers associated with FGFR3 mutations are suspected.
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