tgif1

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tgif1

Official Full Name TGFB-induced factor homeobox 1
Background Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE). Inhibits the 9-cis-retinoic acid dependent RXR alpha transcription activation of the retinoic acid responsive element. Active transcriptional corepressor of SMAD2. Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures. May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down modulation of the RXR alpha activities.
Synonyms TGIF1; TGFB-induced factor homeobox 1; HPE4, TGFB induced factor (TALE family homeobox) , TGIF; homeobox protein TGIF1; homeobox protein TGIF; 5-TG-3 interacting factor; 5-TG-3-interacting factor 1; TALE homeobox TG-interacting factor; transforming growt
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TGIF1-1114HCL Recombinant Human TGIF1 293 Cell Lysate HEK293 N/A
    Human TGIF1-1115HCL Recombinant Human TGIF1 293 Cell Lysate HEK293 N/A
    Human TGIF1-1116HCL Recombinant Human TGIF1 293 Cell Lysate HEK293 N/A
    Human TGIF1-1117HCL Recombinant Human TGIF1 293 Cell Lysate HEK293 N/A
    Human TGIF1-31143TH Recombinant Human TGIF1 E.coli N/A
    Human TGIF1-4324H Recombinant Human TGIF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TGIF1-589H Recombinant Human TGIF1 Protein, His-tagged E.coli His
    Human TGIF1-590H Recombinant Human TGIF1 Protein, His-tagged E.coli His
    Human TGIF1-591H Recombinant Human TGIF1 Protein, His-tagged E.coli His
    Human TGIF1-592H Recombinant Human TGIF1 Protein, His-tagged E.coli His
    Human TGIF1-593H Recombinant Human TGIF1 Protein, His-tagged E.coli His
    Human TGIF1-594H Recombinant Human TGIF1 Protein, His-tagged E.coli His
    Mouse TGIF1-16710M Recombinant Mouse TGIF1 Protein Mammalian Cell His
    Mouse Tgif1-6394M Recombinant Mouse Tgif1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Chicken TGIF1-6931C Recombinant Chicken TGIF1 Mammalian Cell His
    Zebrafish TGIF1-9970Z Recombinant Zebrafish TGIF1 Mammalian Cell His

    tgif1 involved in several pathways and played different roles in them. We selected most pathways tgif1 participated on our site, such as TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with tgif1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TGF-beta signaling pathway PPP2R1A; TGFBR1A; NOG2; TGFB2; BMP8B; NOG; BAMBIA; MAPK3; ID2A; TGFBR2

    tgif1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, chromatin binding, co-SMAD binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tgif1 itself. We selected most functions tgif1 had, and list some proteins which have the same functions with tgif1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II core promoter proximal region sequence-specific DNA binding POU2F2; MAFB; PGR; MYC; SOX1; RBPJL; OTX2; NEUROD6; DLX4; MYOD1
    chromatin binding PRIMPOL; TFAP2A; HDAC3; SAFB; SOX15; HMG20B; DLX2; GABPA; PATZ1; SALL1
    co-SMAD binding GATA4; TGIF1; SMAD1; FOXH1; CITED1; TRIM33; SMAD6; SMAD3; USP9X; SMAD2
    protein binding TBL1XR1; LSM8; RIC8A; NEUROG1; POLD2; ECSIT; GSN; MARVELD3; MLLT1; FLT1
    transcription corepressor activity WWTR1; THRB; CTBP2A; SSX4; NFKBIL2; E2F8; ZFPM1; CSDA; BATF3; DMAP1
    transcription factor activity, sequence-specific DNA binding TBPL2; STAT5B; NR4A2B; MYC; HLFA; OTX1A; ZNF193; KDM5A; FOXP3; TEAD1
    transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding REST; BCL11A; NKX6-1; CTCF; NFIL3-6; NKX6-2; TFAP2A; ASCL2; SP3; ZFP746

    tgif1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tgif1 here. Most of them are supplied by our site. Hope this information will be useful for your research of tgif1.

    CTBP2; MDFI; LGALS8; PML

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