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Recombinant Human TGIF1 Protein, His-tagged

Cat.No. : TGIF1-591H
Product Overview : Recombinant Human TGIF1, transcript variant 3, fused with His tag at N-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described.
Source : E. coli
Species : Human
Tag : His
Form : 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 29.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TGIF1 TGFB-induced factor homeobox 1 [ Homo sapiens ]
Official Symbol : TGIF1
Synonyms : TGIF1; TGFB-induced factor homeobox 1; HPE4, TGFB induced factor (TALE family homeobox) , TGIF; homeobox protein TGIF1; homeobox protein TGIF; 5-TG-3 interacting factor; 5-TG-3-interacting factor 1; TALE homeobox TG-interacting factor; transforming growth factor-beta-induced factor; HPE4; TGIF; MGC5066; MGC39747;
Gene ID : 7050
mRNA Refseq : NM_003244
Protein Refseq : NP_003235
MIM : 602630
UniProt ID : Q15583

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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