thbs4

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thbs4

Official Full Name thrombospondin 4
Background The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. Studies of the rat counterpart suggest that this protein may be involved in local signaling in the developing and adult nervous system.
Synonyms THBS4; thrombospondin 4; thrombospondin-4; TSP4
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human THBS4-114H Recombinant Human THBS4 protein, T7/His-tagged E.coli T7/His
    Human THBS4-121H Recombinant Human THBS4, GST-tagged Wheat Germ GST
    Human THBS4-1774HCL Recombinant Human THBS4 cell lysate N/A
    Human THBS4-507H Recombinant Human Thrombospondin 4, His-tagged CHO His
    Human THBS4-8256H Recombinant Human THBS4 protein, His & GST-tagged E.coli His/GST
    Mouse Thbs4-120M Recombinant Mouse Thbs4, His-tagged CHO His
    Mouse Thbs4-8257M Recombinant Mouse Thbs4 protein, His & GST-tagged E.coli His/GST
    Rat Thbs4-8258R Recombinant Rat Thbs4 protein, His & GST-tagged E.coli His/GST

    thbs4 involved in several pathways and played different roles in them. We selected most pathways thbs4 participated on our site, such as Phagosome, PIK-Akt signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with thbs4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome BMA1; CTSL1B; FAM49BA; ITGAV; RAC1A; FCAR; NCF2; CALR3B; TUBA8L; HLA-DMB
    PIK-Akt signaling pathway INS; YWHAE; FGF19; MCL1; YWHAG; HSP90AA1; GYS1; FGF20; Ifna11; FGF11
    Focal adhesion VWF; PIK3R2; PAK6; BIRC3; PRKCBA; PAK4; COL11A1A; VAV3; PIK3R1; ITGA9
    ECM-receptor interaction TNR; CD36; COL11A1A; LAMC1; Npnt; COL2A1B; ITGA3; FN1; ITGA9; LAMC2
    Malaria IL1B; SELP; KLRK1; CD40; HBA-A2; SDC2; HBA1; TLR9; MYD88; ITGB2

    thbs4 has several biochemical functions, for example, calcium ion binding, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by thbs4 itself. We selected most functions thbs4 had, and list some proteins which have the same functions with thbs4. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PCDHGA6; SYT12; KCNIP3; CRB1; SCUBE3; EPDL1; NKD1; SCUBE2; DST; CHP2
    growth factor activity IL10; BMP7; FGF6B; VEGFAB; MSTNB; GDF2; GDF6B; NRG1; NTF7; MDK
    heparin binding ANG; PCOLCE; AZU1; CCL7; ELANE; CXCL13; EPYC; WISP2; THBS4; APPB
    integrin binding FN1; ADAM22; MMP14; LAMB1; ICAM3; S1PR3; S1PR2; ITGB5; COL5A1; ITGB1BP1
    protein binding FRMPD1; CHUK; FIS1; BCL2L11; TMSB4X; PI4K2A; CSNK1D; GHRL; PSMC6; ADSS

    thbs4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with thbs4 here. Most of them are supplied by our site. Hope this information will be useful for your research of thbs4.

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