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TM4SF1

  • Official Full Name

    transmembrane 4 L six family member 1

  • Overview

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008]
  • Synonyms

    TM4SF1; transmembrane 4 L six family member 1; L6; H-L6; M3S1; TAAL6; transmembrane 4 L6 family member 1; tumor-associated antigen L6; transmembrane 4 superfamily member 1; membrane component chromosome 3 surface marker 1; membrane component, chromosome 3, surface marker 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TM4SF1-2941H Active Recombinant Human TM4SF1 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human TM4SF1-2942H Active Recombinant Human TM4SF1 Full Length Transmembrane protein(MNP) HEK293 N/A
Human TM4SF1-3262H Recombinant Human TM4SF1, GST-tagged E.coli GST 1-202aa
Human TM4SF1-667HCL Recombinant Human TM4SF1 lysate HEK293 N/A
Human TM4SF1-981H Active Recombinant Human TM4SF1 Transmembrane protein(VLPs) HEK293 N/A Met1-Cys202
Human TM4SF1-1857H Recombinant Human TM4SF1 Protein (115-161 aa), His-tagged Yeast His 115-161 aa
Mouse TM4SF1-16838M Recombinant Mouse TM4SF1 Protein Mammalian Cell His
Mouse TM4SF1-9245M-B Recombinant Mouse TM4SF1 Protein Pre-coupled Magnetic Beads HEK293
Mouse TM4SF1-9245M Recombinant Mouse TM4SF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL10548HF Recombinant Full Length Human Transmembrane 4 L6 Family Member 1(Tm4Sf1) Protein, His-Tagged E.coli expression system His Full Length (1-202)
Mus musculus (Mouse) RFL19447MF Recombinant Full Length Mouse Transmembrane 4 L6 Family Member 1(Tm4Sf1) Protein, His-Tagged E.coli expression system His Full Length (1-202)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL22138PF Recombinant Full Length Pongo Abelii Transmembrane 4 L6 Family Member 1(Tm4Sf1) Protein, His-Tagged E.coli expression system His Full Length (1-202)
Rhesus Macaque TM4SF1-4740R Recombinant Rhesus monkey TM4SF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TM4SF1-4554R Recombinant Rhesus Macaque TM4SF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TM4SF1-4554R-B Recombinant Rhesus Macaque TM4SF1 Protein Pre-coupled Magnetic Beads HEK293
Chicken TM4SF1-4874C Recombinant Chicken TM4SF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TM4SF1 Related Articles

TM4SF1 involved in several pathways and played different roles in them. We selected most pathways TM4SF1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TM4SF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TM4SF1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by TM4SF1 itself. We selected most functions TM4SF1 had, and list some proteins which have the same functions with TM4SF1. You can find most of the proteins on our site.

Function Related Protein
molecular_functionCHCHD6A;DSCR4;REG3D;D1BWG0212E;NAP1L4B;VMN1R155;FAM134A;PRRG4;TRIM6

TM4SF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TM4SF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TM4SF1.

HSPA8; DNAJA1; TUBA4A; DDR1; malS

Choi, SI; Kim, SY; et al. TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1. ONCOTARGET 5:9823-9837(2014).
Lin, CI; Merley, A; et al. TM4SF1: a new vascular therapeutic target in cancer. ANGIOGENESIS 17:897-907(2014).
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