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Official Full Name transmembrane protease, serine 4
Background This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms TMPRSS4; transmembrane protease, serine 4; transmembrane protease serine 4; membrane type serine protease 2; MT SP2; TMPRSS3; transmembrane serine protease 3; type II membrane serine protease; UNQ776/PRO1570; TMPRSS 4; OTTHUMP00000225915; OTTHUMP00000225916; OTTHUMP00000225917; OTTHUMP00000225918; OTTHUMP00000225921; OTTHUMP00000233153; channel-activating protease 2; membrane-type serine protease 2; CAPH2; MT-SP2
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • SUMO
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TMPRSS4-3308H Recombinant Human TMPRSS4, GST-tagged E.coli GST
    Human TMPRSS4-337H Recombinant Human TMPRSS4 Protein, His-tagged E.coli His
    Human TMPRSS4-3839H Recombinant Human TMPRSS4, MYC/DDK-tagged HEK293 Myc/DDK
    Human TMPRSS4-4214H Recombinant Human TMPRSS4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TMPRSS4-6343H Recombinant Human TMPRSS4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TMPRSS4-908HCL Recombinant Human TMPRSS4 293 Cell Lysate HEK293 N/A
    Mouse TMPRSS4-17121M Recombinant Mouse TMPRSS4 Protein Mammalian Cell His
    Mouse Tmprss4-3309M Recombinant Mouse Tmprss4 Protein, His/SUMO-tagged E.coli His/SUMO
    Mouse Tmprss4-6527M Recombinant Mouse Tmprss4 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    tmprss4 involved in several pathways and played different roles in them. We selected most pathways tmprss4 participated on our site, such as Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with tmprss4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Influenza A HSPA8; TNFRSF10D; Ifna11; PIK3CD; MAVS; ACTB; PRSS3; IFNA13; MAP2K1; EIF2AK3

    tmprss4 has several biochemical functions, for example, protein binding, scavenger receptor activity, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by tmprss4 itself. We selected most functions tmprss4 had, and list some proteins which have the same functions with tmprss4. You can find most of the proteins on our site.

    Function Related Protein
    scavenger receptor activity ABHD1; LOXL4; LGALS3BPB; PRG4; ACKR4; TMPRSS13B; MSR1; SCARF2; CD163L1; LOXL2
    serine-type endopeptidase activity MASP1; PARL; LTF; HTRA1; LPA; HTRA4; CTRL; TMPRSS11E; TMPRSS13B; TMPRSS11G

    tmprss4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tmprss4 here. Most of them are supplied by our site. Hope this information will be useful for your research of tmprss4.

    CCDC155; TMEM79

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