Recombinant Human TNFRSF10D
Cat.No. : | TNFRSF10D-1693H |
- Specification
- Gene Information
- Related Products
Cat. No. : | TNFRSF10D-1693H |
Description : | TNF-related apoptosis-inducing ligand receptor 4 (TRAIL R4) is a decoy receptor that negatively regulate TRAIL-induced cytotoxicity by competing for ligand binding with TRAIL-R1 and TRAIL-R2.1 TRAIL R4 is expressed mainly on CD8+ and NK cells and induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4 contains partially truncated death domain and therefore is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. |
Molecular Weight : | The predicted molecular weight of Recombinant Human TRAIL R4 is Mr 44.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain [ Homo sapiens ] |
Synonyms : | TNFRSF10D; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; DCR2; CD264; TRUNDD; TRAILR4; tumor necrosis factor receptor superfamily, member 10d; TRAIL receptor 4; decoy receptor 2; decoy with truncated death domain; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; DcR2; TRAIL-R4; CD264 antigen; TNF-related apoptosis-inducing ligand receptor 4 |
Gene ID : | 8793 |
mRNA Refseq : | NM_003840 |
Protein Refseq : | NP_003831 |
MIM : | 603614 |
UniProt ID : | Q9UBN6 |
Chromosome Location : | 8p21 |
Pathway : | Apoptosis; Cytokine-cytokine receptor interaction; Natural killer cell mediated cytotoxicity |
Function : | protein binding; transmembrane receptor activity |
Products Types
◆ Recombinant Protein | ||
TNFRSF10D-464H | Recombinant Human TNFRSF10D Protein, His-tagged | +Inquiry |
TNFRSF10D-465H | Recombinant Human TNFRSF10D Protein, Fc-tagged | +Inquiry |
TNFRSF10D-4495H | Recombinant Human TNFRSF10D Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF10D-309H | Recombinant Human TNFRSF10D Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
TNFRSF10D-1641R | Recombinant Rhesus Monkey TNFRSF10D Protein | +Inquiry |
◆ Lysates | ||
TNFRSF10D-2459HCL | Recombinant Human TNFRSF10D cell lysate | +Inquiry |
TNFRSF10D-1188CCL | Recombinant Cynomolgus TNFRSF10D cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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