TRIM13

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TRIM13

Official Full Name tripartite motif containing 13
Background This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms TRIM13; tripartite motif containing 13; ret finger protein 2 , RFP2, tripartite motif containing 13; E3 ubiquitin-protein ligase TRIM13; DLEU5; Leu5; RNF77; ret finger protein 2; RING finger protein 77; CLL-associated RING finger; tripartite motif protei
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM13-2018H Recombinant Human TRIM13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TRIM13-795HCL Recombinant Human TRIM13 293 Cell Lysate HEK293 N/A
    Mouse Trim13-6644M Recombinant Mouse Trim13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat TRIM13-6270R Recombinant Rat TRIM13 Protein Mammalian Cell His
    Zebrafish TRIM13-2783Z Recombinant Zebrafish TRIM13 Mammalian Cell His

    TRIM13 involved in several pathways and played different roles in them. We selected most pathways TRIM13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    TRIM13 has several biochemical functions, for example, ligase activity, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM13 itself. We selected most functions TRIM13 had, and list some proteins which have the same functions with TRIM13. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity RNF38; TRIML1; RNF114; UBE4B; TRIM39; ATG10; UBE2D1A; IRF2BP1; RNF2; CBLL1
    protein binding C1QB; BAHD1; FHL1; GRB10; MEF2D; DSTN; CCNA2; SLC22A7; TNKS2; SUGP1
    signal transducer activity GNAZ; DRD2B; OLFR488; GNA15.1; CBL; GMFB; GPR89; GPR124; ACKR3B; CBLB
    ubiquitin-protein transferase activity FBXW2; FBXO21; FBXW11; FBXL14A; TNFAIP3; FBXL3; PEX12; FBXL7; TRIM17; TRIM33
    zinc ion binding MMP16; PGLYRP2; ZNF207; ZBBX; MSRB1; APOBEC3C; FBXO40; BMP1A; Car9; BRF1

    TRIM13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM13.

    FLJ13057

    Gatt, ME; Takada, K; et al. TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity. BRITISH JOURNAL OF HAEMATOLOGY 162:210-220(2013).
    Zoumpoulidou, G; Broceno, C; et al. Role of the Tripartite Motif Protein 27 in Cancer Development. JOURNAL OF THE NATIONAL CANCER INSTITUTE 104:941-952(2012).

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