|Official Full Name||TSC22 domain family, member 1|
|Background||This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.|
|Synonyms||TSC22D1; TSC22 domain family, member 1; TGFB1I4, transforming growth factor beta 1 induced transcript 4; TSC22 domain family protein 1; MGC17597; TSC22; Cerebral protein 2; DKFZp686O19206; Hucep 2; Hucep2; KIAA1994; OTTHUMP00000040978; Regulatory protein TSC 22; Regulatory protein TSC22; RP11 269C23.2; TGFB stimulated clone 22 homolog; TGFB1I4; Transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta 1 induced transcript 4 protein; Transforming growth factor beta stimulated protein TSC 22; TSC 22; TSC22 domain family 1 isoform 2; TSC22 domain family member 1; regulatory protein TSC-22; TGFbeta-stimulated clone 22; TGFB-stimulated clone 22 homolog; transcriptional regulator TSC-22; transforming growth factor beta-stimulated protein TSC-22; transforming growth factor beta-1-induced transcript 4 protein; Ptg-2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
TSC22D1 involved in several pathways and played different roles in them. We selected most pathways TSC22D1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSC22D1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
TSC22D1 has several biochemical functions, for example, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSC22D1 itself. We selected most functions TSC22D1 had, and list some proteins which have the same functions with TSC22D1. You can find most of the proteins on our site.
|protein binding||CRYBB1; CD69; ZNF180; TERT; CXXC1; DSTN; FAM108A1; NECAB2; TNFRSF1A; BEND3|
|transcription factor activity, sequence-specific DNA binding||NR4A2A; FOXD1L; ZFP13; GABPA; IKZF4; ZNF383; ZIC5; RXRBB; NANOG; FOXO4|
TSC22D1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSC22D1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSC22D1.
TPT1; WDYHV1; APLP1; SETDB1; CCDC90B; a2j422_human; 4504555