Recombinant Human UBA1, GST-tagged
Cat.No. : | UBA1-832H |
Product Overview : | Recombinant full-length human UBA1 (UBE1) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | UBA1 or ubiquitin-like modifier activating enzyme 1 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins and catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. UBE1 is able to transfer ubiquitin to a wide range of E2 substrates. UBA1 protein may participate in DNA topoisomerase-2 activity. UBA1 complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~145 kDa |
Protein length : | Full length |
Purity : | >95% |
Applications : | Western Blot |
Stability : | 1yr at –70°C from date of shipment |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1ug/ul |
Gene Name : | UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ] |
Official Symbol : | UBA1 |
Synonyms : | UBA1; ubiquitin-like modifier activating enzyme 1; A1S9T, GXP1, UBE1, ubiquitin activating enzyme E1 , ubiquitin activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing); ubiquitin-like modifier-activating enzyme 1; POC20; POC20 centriolar protein homolog (Chlamydomonas); ubiquitin activating enzyme E1 homolog (yeast); UBE1X; POC20 centriolar protein homolog; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; MGC4781; |
Gene ID : | 7317 |
mRNA Refseq : | NM_003334 |
Protein Refseq : | NP_003325 |
MIM : | 314370 |
UniProt ID : | P22314 |
Chromosome Location : | Xp11.23 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Parkinsons disease, organism-specific biosystem; |
Function : | ATP binding; ligase activity; nucleotide binding; protein binding; small protein activating enzyme activity; |
Products Types
◆ Recombinant Protein | ||
UBA1-7333H | Recombinant Human UBA1 protein(Ser2-Arg1058), His&GST-tagged | +Inquiry |
Uba1-6764M | Recombinant Mouse Uba1 Protein, Myc/DDK-tagged | +Inquiry |
UBA1-212H | Recombinant Human UBA1 Protein, MYC/DDK-tagged | +Inquiry |
UBA1-337H | Recombinant Human UBA1 Protein, His-tagged | +Inquiry |
UBA1-264H | Recombinant Human UBA1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Lysates | ||
UBA1-420HCL | Recombinant Human UBA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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