Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human UBA1

Cat.No. : UBA1-105H
Product Overview : Recombinant Human UBA1, was expressed in E.coli.
  • Specification
  • Gene Information
  • Related Products
Source : E.coli
Species : Human
Form : Liquid. 50mM Tris Buffer, pH 8.0, 100mM NaCl, 10% glycerol.
Bio-activity : Typical enzyme concentration of 5nM – 100nM is used for in vitro conjugation, depending on conditions
Molecular Mass : 118kDa
Purity : >95% by SDS-PAGE
Storage : Store at -80℃. Avoid repeated freeze/thaw cycles.
Gene Name : UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ]
Official Symbol : UBA1
Synonyms : UBA1; ubiquitin-like modifier activating enzyme 1; A1S9T, GXP1, UBE1, ubiquitin activating enzyme E1 , ubiquitin activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing); ubiquitin-like modifier-activating enzyme 1; POC20; POC20 centriolar protein homolog (Chlamydomonas); ubiquitin activating enzyme E1 homolog (yeast); UBE1X; POC20 centriolar protein homolog; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; MGC4781;
Gene ID : 7317
mRNA Refseq : NM_003334
Protein Refseq : NP_003325
MIM : 314370
UniProt ID : P22314
Chromosome Location : Xp11.23
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Function : ATP binding; ligase activity; nucleotide binding; protein binding; small protein activating enzyme activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Are there any clinical trials involving UBA1 as a target? 04/20/2023

Some early-phase clinical trials are exploring UBA1 as a potential target in the context of ALS and cancer.

How can UBA1 be targeted for therapeutic purposes? 09/19/2020

Targeting UBA1 with small molecules or gene therapy may provide a potential avenue for treating UBA1-related diseases.

How does UBA1 function in the cell? 12/04/2017

UBA1 activates ubiquitin, a small protein that tags other proteins for degradation by the proteasome.

What diseases are associated with UBA1 dysfunction? 07/19/2017

UBA1 dysfunction has been linked to neurodegenerative diseases like amyotrophic lateral sclerosis (ALS) and certain types of cancer.

Can UBA1 be a diagnostic marker for ALS? 08/16/2016

Research suggests that altered UBA1 levels in the cerebrospinal fluid may be a potential biomarker for ALS diagnosis.

Customer Reviews (3)

Write a review
Reviews
07/02/2022

    The UBA1 protein comes highly recommended for its outstanding performance in various experimental applications.

    07/07/2019

      In ELISA assays, it has consistently exhibited exceptional reliability and accuracy, providing precise and reproducible results.

      05/13/2017

        Their prompt and knowledgeable guidance has been instrumental in effectively addressing my queries and optimizing the utilization of the UBA1 protein in my studies.

        Ask a Question for All UBA1 Products

        Required fields are marked with *

        My Review for All UBA1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends