Active Recombinant Human UBA1
Cat.No. : | UBA1-105H |
Product Overview : | Recombinant Human UBA1, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Source : | E.coli |
Species : | Human |
Form : | Liquid. 50mM Tris Buffer, pH 8.0, 100mM NaCl, 10% glycerol. |
Bio-activity : | Typical enzyme concentration of 5nM – 100nM is used for in vitro conjugation, depending on conditions |
Molecular Mass : | 118kDa |
Purity : | >95% by SDS-PAGE |
Storage : | Store at -80℃. Avoid repeated freeze/thaw cycles. |
Gene Name : | UBA1 ubiquitin-like modifier activating enzyme 1 [ Homo sapiens ] |
Official Symbol : | UBA1 |
Synonyms : | UBA1; ubiquitin-like modifier activating enzyme 1; A1S9T, GXP1, UBE1, ubiquitin activating enzyme E1 , ubiquitin activating enzyme E1 (A1S9T and BN75 temperature sensitivity complementing); ubiquitin-like modifier-activating enzyme 1; POC20; POC20 centriolar protein homolog (Chlamydomonas); ubiquitin activating enzyme E1 homolog (yeast); UBE1X; POC20 centriolar protein homolog; UBA1, ubiquitin-activating enzyme E1 homolog A; A1S9T and BN75 temperature sensitivity complementing; A1S9; A1ST; GXP1; UBE1; A1S9T; AMCX1; SMAX2; UBA1A; MGC4781; |
Gene ID : | 7317 |
mRNA Refseq : | NM_003334 |
Protein Refseq : | NP_003325 |
MIM : | 314370 |
UniProt ID : | P22314 |
Chromosome Location : | Xp11.23 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem; Parkinsons disease, organism-specific biosystem; |
Function : | ATP binding; ligase activity; nucleotide binding; protein binding; small protein activating enzyme activity; |
Products Types
◆ Recombinant Protein | ||
UBA1-264H | Recombinant Human UBA1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
UBA1-337H | Recombinant Human UBA1 Protein, His-tagged | +Inquiry |
UBA1-6041R | Recombinant Rat UBA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Uba1-6764M | Recombinant Mouse Uba1 Protein, Myc/DDK-tagged | +Inquiry |
UBA1-7333H | Recombinant Human UBA1 protein(Ser2-Arg1058), His&GST-tagged | +Inquiry |
◆ Lysates | ||
UBA1-420HCL | Recombinant Human UBA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSome early-phase clinical trials are exploring UBA1 as a potential target in the context of ALS and cancer.
Targeting UBA1 with small molecules or gene therapy may provide a potential avenue for treating UBA1-related diseases.
UBA1 activates ubiquitin, a small protein that tags other proteins for degradation by the proteasome.
UBA1 dysfunction has been linked to neurodegenerative diseases like amyotrophic lateral sclerosis (ALS) and certain types of cancer.
Research suggests that altered UBA1 levels in the cerebrospinal fluid may be a potential biomarker for ALS diagnosis.
Customer Reviews (3)
Write a reviewThe UBA1 protein comes highly recommended for its outstanding performance in various experimental applications.
In ELISA assays, it has consistently exhibited exceptional reliability and accuracy, providing precise and reproducible results.
Their prompt and knowledgeable guidance has been instrumental in effectively addressing my queries and optimizing the utilization of the UBA1 protein in my studies.
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