UL16-binding proteins (ULBP) or retinoic acid early transcripts-1 (RAET1) are ligands to the activating receptor, NKG2D. Ten members of the human ULBP/RAET1 gene family have been identified to encode for potentially functional proteins, and have tissue-s
ULBP1 involved in several pathways and played different roles in them. We selected most pathways ULBP1 participated on our site, such as Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with ULBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
ULBP1 has several biochemical functions, for example, natural killer cell lectin-like receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ULBP1 itself. We selected most functions ULBP1 had, and list some proteins which have the same functions with ULBP1. You can find most of the proteins on our site.
ULBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ULBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ULBP1.
Fujita, H; Hatanaka, Y; et al. Immunohistochemical Validation and Expression Profiling of NKG2D Ligands in a Wide Spectrum of Human Epithelial Neoplasms. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 63:217-227(2015).
Seidel, E; Le, VTK; et al. Dynamic Co-evolution of Host and Pathogen: HCMV Downregulates the Prevalent Allele MICA*008 to Escape Elimination by NK Cells. CELL REPORTS 10:968-982(2015).
