UQCRC2

  • Official Full Name

    ubiquinol-cytochrome c reductase core protein II

  • Overview

    Ubiquinol-cytochrome c reductase core protein II is a protein that in humans is encoded by the UQCRC2 gene. Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), whi

  • Synonyms

    UQCRC2;ubiquinol-cytochrome c reductase core protein II;cytochrome b-c1 complex subunit 2, mitochondrial;QCR2;UQCR2;mitochondrial;Complex III subunit 2;Core protein II;Cytochrome b-c1 complex subunit 2;EC 1.10.2.2;QCR2_HUMAN;Ubiquinol cytochrome c reductase complex core protein 2 mitochondrial;Ubiquinol cytochrome c reductase core protein II;Ubiquinol-cytochrome-c reductase complex core protein 2

Recombinant Proteins

  • Mouse
  • Human
  • Rhesus macaque
  • Rat
  • Mammalian Cells
  • E.coli
  • HEK293
  • HT-1080
  • His
  • T7
  • Non
  • Avi
  • Fc

    Involved Pathway

    UQCRC2 involved in several pathways and played different roles in them. We selected most pathways UQCRC2 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UQCRC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Non-alcoholic fatty liver disease (NAFLD) COX7A2L,NDUFA4L2,MAPK9,NDUFB8,PIK3R5,UQCRH,MAP3K11,INS2,LEPR,SDHC
    Huntingtons disease CYCS,NDUFB6,DNALC4,DNALC1,NDUFB5,NDUFA8,NDUFA2,NDUFS5,COX7A2L,TP53
    Cardiac muscle contraction ATP1B3B,CACNG1A,MYL2B,ATP2A2,FXYD2,ATP1A3A,RYR2,COX6C,ATP1A2,CACNB2
    Oxidative phosphorylation ATP6V1E2,NDUFS2,NDUFAB1A,ATP6V1H,ATP6V1D,ATP6V0B,UQCRB,UQCRQ,NDUFA5,NDUFA3
    Parkinsons disease NDUFB4,COX7A2,ATP5E,ATP5G1,Atp5g2,NDUFA8,DRD1A,COX7B,SDHD,SDHA
    Metabolic pathways ALDH18A1,PPAT,NOS2B,NDUFV1,COX6A1,ATP5C1,B4GALT3,COX17,MTHFR,UQCR10
    Alzheimers disease APH1C,FADD,NDUFB5,PSENEN,PPP3CB,NDUFB7,COX7A2L,PPP3R2,BACE1,COX6C

    Protein Function

    UQCRC2 has several biochemical functions, for example, metalloendopeptidase activity,protein binding,protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UQCRC2 itself. We selected most functions UQCRC2 had, and list some proteins which have the same functions with UQCRC2. You can find most of the proteins on our site.

    Function Related Protein
    protein complex binding TRAF2,EP300,TULP2,OTOF,PPP4C,PTPRF,CDK2,MTHFR,CDK5RAP1,MYSM1
    zinc ion binding LIMS3,ZMAT3,PPARDB,ZDHHC5,TRIM14,ADAMTS20,RBM14A,TLL2,ADH4,UQCRC1
    metalloendopeptidase activity ADAMTS10,PAPLN,PAPPAB,MMP15,MMP14B,NLN,MMP30,MMP1A,ADAMTS7,ADAM32
    protein binding C7orf49,AKR7A3,TEAD3,IGFBP5,DCTN5,SOX10,C9orf24,PIP5K1A,GOLPH3,SNIP1

    Interacting Protein

    UQCRC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UQCRC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UQCRC2.

    UQCRC1;CACNA1A;a8k1f4_human;HLA-B;ARF6;15-deoxy-delta(12,14;RNH1;ATF2;Csk;HTT;ICT1;Ddb1;Rmdn3;P;HUWE1;Ercc6l;SLX1A

    Resources

    References

    • Hu, WH; Hausmann, ON; et al. Identification and characterization of a novel Nogo-interacting mitochondrial protein (NIMP). JOURNAL OF NEUROCHEMISTRY 81:36-45(2002).

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All UQCRC2 Products

    Required fields are marked with *

    My Review for All UQCRC2 Products

    Required fields are marked with *