Human UQCRC2 Knockdown Cell Lysate

• Cat.No.: UQCRC2-513HKCL
• Product Overview: WB-validated UQCRC2 Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 48 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg UQCRC2 KD HT-1080 cell lysate
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: UQCRC2 ubiquinol-cytochrome c reductase core protein II [ Homo sapiens (human) ]
• Official Symbol: UQCRC2
• Synonyms: UQCRC2; ubiquinol-cytochrome c reductase core protein II; cytochrome b-c1 complex subunit 2, mitochondrial; QCR2; UQCR2; core protein II; complex III subunit 2; ubiquinol-cytochrome-c reductase complex core protein 2
• Gene ID: 7385
• mRNA Refseq: NM_003366
• Protein Refseq: NP_003357
• MIM: 191329
• UniProt ID: P22695