Recombinant Human Ubiquinol-Cytochrome C Reductase Core Protein II, T7-tagged

• Cat.No.: UQCRC2-3008H
• Product Overview: Recombinant Human UQCRC2 protein was expressed in E.coli with T7-tag at the N-terminus. The molecular weight is 48443 Da(453 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Description: Ubiquinol-cytochrome c reductase core protein II is a protein that in humans is encoded by the UQCRC2 gene. Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial cytochrome b) and ten nuclear genes: UQCRC1, UQCRC2, Cytochrome c1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and "Rieske-associated protein".
• Sequences of amino acids: 1-453 aa
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
• Purity: 95%

Gene Information

• Gene Name: UQCRC2 ubiquinol-cytochrome c reductase core protein II [ Homo sapiens ]
• Synonyms: QCR2; UQCR2; cytochrome b-c1 complex subunit 2, mitochondrial; core protein II; complex III subunit 2; ubiquinol-cytochrome-c reductase complex core protein 2
• Gene ID: 7385
• mRNA Refseq: NM_003366
• Protein Refseq: NP_003357
• MIM: 191329
• UniProt ID: P22695
• Chromosome Location: 16p12
• Pathway: Alzheimer"s disease; Cardiac muscle contraction; Huntington"s disease; Metabolic pathways; Oxidative phosphorylation; Parkinson"s disease; Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins
• Function: catalytic activity; metal ion binding; metalloendopeptidase activity; protein binding; protein complex binding; zinc ion binding