USP45 involved in several pathways and played different roles in them. We selected most pathways USP45 participated on our site, such as DNA Repair, Formation of Incision Complex in GG-NER, Global Genome Nucleotide Excision Repair (GG-NER), which may be useful for your reference. Also, other proteins which involved in the same pathway with USP45 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| DNA Repair |
TDP2B; RAD18; BAZ1B; ZBTB32; TFPT; CHD1L; COPS7B; PPP4R2; DTL; GPS1 |
| Formation of Incision Complex in GG-NER |
PIAS3; DDB2; CHD1L; CETN2; RNF111; PARP2; USP45; DDB1 |
| Global Genome Nucleotide Excision Repair (GG-NER) |
COPS7B; ACTR5; USP45; CHD1L; INO80; DDB2; TFPT; COPS7A; COPS6; YY1A |
| Nucleotide Excision Repair |
ERCC2; LIG1; GPS1; YY1A; COPS5; COPS2; GTF2H2; ERCC3; PPIE; COPS7B |
USP45 has several biochemical functions, for example, cysteine-type endopeptidase activity, ubiquitin-specific protease activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP45 itself. We selected most functions USP45 had, and list some proteins which have the same functions with USP45. You can find most of the proteins on our site.
| Function |
Related Protein |
| cysteine-type endopeptidase activity |
CASPB; CTSBB; USP48; USP43; CTSJ; CTSSB.1; USP12; CTSO; CFLARA; CASP3B |
| ubiquitin-specific protease activity |
ATXN3L; USP49; ATXN3; USP40; COPS5; OTUB1A; USP17L2; TNFAIP3; OTUB2; USP47 |
| zinc ion binding |
CA3; MAN2B2; S100A3; AKT1S1; C11orf54; UQCRC2; CA13; NR6A1; PJA1; RORCA |
USP45 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP45 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP45.
RTCA; MYL12B; FARS2; IGKV4-1; CDK1; FLNA; MYH9; MYH10; RBMX; PIK3CG; YLPM1; MYL6; POLR2G; SAFB; SF3A2; SRBD1; ZFR; TMOD3; GLTSCR2; RALY
Zadravec, P; Strukelj, B; et al. Improvement of LysM-Mediated Surface Display of Designed Ankyrin Repeat Proteins (DARPins) in Recombinant and Nonrecombinant Strains of Lactococcus lactis and Lactobacillus Species. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 81:2098-2106(2015).
Yang, XQ; Zhao, YG; et al. The protective effect of recombinant Lactococcus lactis oral vaccine on a Clostridium difficile-infected animal model. BMC GASTROENTEROLOGY 13:-(2013).
