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USP6

Official Full Name

ubiquitin specific peptidase 6 (Tre-2 oncogene)
Overview

Ubiquitin carboxyl-terminal hydrolase 6 is an enzyme that in humans is encoded by the USP6 gene.
Synonyms

USP6; ubiquitin specific peptidase 6 (Tre-2 oncogene); HRP1, ubiquitin specific protease 6 (Tre 2 oncogene); ubiquitin carboxyl-terminal hydrolase 6; Tre 2; Tre2; TRE17; Deubiquitinating enzyme 6; HRP1; Proto-oncogene TRE-2; Ubiquitin specific protease 6; Ubiquitin thiolesterase 6; Ubiquitin-specific-processing protease 6; UBP6_HUMAN; tre-2 oncogene; OTTHUMP00000125301; hyperpolymorphic gene 1; ubiquitin thioesterase 6; ubiquitin specific peptidase 6-; ubiquitin-specific protease; Tre-2; USP6-short;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	USP6-154H	Active Recombinant Human USP6, GST-tagged	Insect Cell	GST		Inquiry
Human	USP6-277H	Recombinant Human USP6, GST-tagged	Wheat Germ	GST		Inquiry
Human	USP6-0356H	Recombinant Human USP6 Protein (K529-Q1406), Tag Free	Insect Cell	No tag	K529-Q1406	Inquiry
Human	USP6-0355H	Recombinant Human USP6 Protein (K529-Q1406), GST tagged	Insect Cell	GST	K529-Q1406	Inquiry

Involved Pathway
Protein Function
Interacting Protein

USP6 involved in several pathways and played different roles in them. We selected most pathways USP6 participated on our site, such as Arf6 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Arf6 signaling events	EGF;USP6;FBXO8;ARAP2;EPHA2;EGFR;ADRB2;IPCEF1;EFNA1

USP6 has several biochemical functions, for example, calmodulin binding, cysteine-type endopeptidase activity, nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP6 itself. We selected most functions USP6 had, and list some proteins which have the same functions with USP6. You can find most of the proteins on our site.

Function	Related Protein
calmodulin binding	MAPKAPK5;TJP1;RYR2;SPTBN1;PPP3CB;UPF3B;ITPKC;MYO1C;MKNK2A
cysteine-type endopeptidase activity	CASP9;USP2;CASP8L1;CASP7;CTSSA;USP1;CTSBA;USP13;CTSM
nucleic acid binding	QKIA;DHX36;RBM24A;Akap17b;ZFP57;AKAP1B;PABPC1L;ZFP507;ZFP787
protein binding	RPS6KA3;DDX11;DNAJB9;DMKN;NKX3;MPPED2;AMY1A;MRPL51;NFAT5
ubiquitin-specific protease activity	DUB1;USP6;USP33;USP28;USP16;USP15;YOD1;FAM105B;VCPIP1

USP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP6.

MDFI; USP32; ATXN7L3; ANKRD44