USP6

  • Official Full Name

    ubiquitin specific peptidase 6 (Tre-2 oncogene)

  • Overview

    Ubiquitin carboxyl-terminal hydrolase 6 is an enzyme that in humans is encoded by the USP6 gene.
  • Synonyms

    USP6; ubiquitin specific peptidase 6 (Tre-2 oncogene); HRP1, ubiquitin specific protease 6 (Tre 2 oncogene); ubiquitin carboxyl-terminal hydrolase 6; Tre 2; Tre2; TRE17; Deubiquitinating enzyme 6; HRP1; Proto-oncogene TRE-2; Ubiquitin specific protease 6; Ubiquitin thiolesterase 6; Ubiquitin-specific-processing protease 6; UBP6_HUMAN; tre-2 oncogene; OTTHUMP00000125301; hyperpolymorphic gene 1; ubiquitin thioesterase 6; ubiquitin specific peptidase 6-; ubiquitin-specific protease; Tre-2; USP6-short;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human USP6-154H Active Recombinant Human USP6, GST-tagged Insect Cell GST
Human USP6-277H Recombinant Human USP6, GST-tagged Wheat Germ GST
Human USP6-0356H Recombinant Human USP6 Protein (K529-Q1406), Tag Free Insect Cell No tag K529-Q1406
Human USP6-0355H Recombinant Human USP6 Protein (K529-Q1406), GST tagged Insect Cell GST K529-Q1406
Human USP6-7121H Recombinant Human USP6 protein(348-535aa), His-KSI-tagged E. coli N-His-KSI 348-535aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein

USP6 involved in several pathways and played different roles in them. We selected most pathways USP6 participated on our site, such as Arf6 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arf6 signaling eventsUSP6;KIF13B;EGFR;ARAP2;EGF;IPCEF1;ADRB2;FBXO8;AGTR1

USP6 has several biochemical functions, for example, calmodulin binding, cysteine-type endopeptidase activity, nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP6 itself. We selected most functions USP6 had, and list some proteins which have the same functions with USP6. You can find most of the proteins on our site.

Function Related Protein
calmodulin bindingRGS4;USP6;MYO9B;PLCB3;DCX;CAMK1G;SRY;KCNN1;MYO3A
cysteine-type endopeptidase activityUSP50;CTSSB.1;MALT1;USP43A;USP17L2;USP51;Casp3;USP40;USP20
nucleic acid bindingPRDM8B;ZFY1;ZFP14;C19orf6;METTL5;ZSCAN4F;ZBTB16A;ZFP622;PNLDC1
protein bindingTCEB1;VIPR1;KCNJ3;ZNF256;MYO1E;KLF4;NTSR1;XAB2;CYCS
ubiquitin-specific protease activityUSP37;VCPIP1;USP7;USP48;OTUB1;STAMBP;OTUD3;OTUD5;USP43

USP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP6.

MDFI; USP32; ATXN7L3; ANKRD44

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