USP9X

  • Official Full Name

    ubiquitin specific peptidase 9, X-linked

  • Overview

    This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Synonyms

    USP9X; ubiquitin specific peptidase 9, X-linked; FAF; FAM; DFFRX; probable ubiquitin carboxyl-terminal hydrolase FAF-X; hFAM; fat facets in mammals; ubiquitin thioesterase FAF-X; deubiquitinating enzyme FAF-X; ubiquitin thiolesterase FAF-X; fat facets protein related, X-linked; fat facets protein-related, X-linked; Drosophila fat facets related, X-linked; ubiquitin-specific protease 9, X chromosome; ubiquitin-specific processing protease FAF-X; ubiquitin-specific-processing protease FAF-X; ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila);

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • Sf21 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Met|His
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human USP9X-184H Active Recombinant Human USP9X, GST-tagged E.coli GST
Human USP9X-658H Active Recombinant Human USP9X, Met&His-tagged Sf21 Insect Cell Met/His
Human USP9X-0343H Recombinant Human USP9X Protein (K1554-N1995), GST tagged E.coli GST K1554-N1995
Human USP9X-0344H Recombinant Human USP9X Protein (K1554-N1995), Tag Free E.coli No tag K1554-N1995
Mouse USP9X-17945M Recombinant Mouse USP9X Protein Mammalian Cell His
Mouse USP9X-9977M Recombinant Mouse USP9X Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse USP9X-9977M-B Recombinant Mouse USP9X Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

USP9X involved in several pathways and played different roles in them. We selected most pathways USP9X participated on our site, such as Downregulation of SMAD2/3:SMAD4 transcriptional activity, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP9X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Downregulation of SMAD2/3:SMAD4 transcriptional activitySKI;SMAD3B;USP9X;SKILB;RNF111;SKIA;PARP1;SKIB;USP9
Gene ExpressionNR1H3;NR2C2;RRN3;FARS2;ZNF350;ZNF43;ZNF454;C2orf49;PUS7
Generic Transcription PathwayZNF773;ZNF221;TRIM28;NR4A2A;NR2E3;COX6C;NR2F6;ZNF213;ZNF584
Signal TransductionGREM2;ROPN1;TRIM33;NF2A;TAAR1;RGR;RNF31;RAMP2;VIP
Signaling by TGF-beta Receptor ComplexNEDD8;STRAP;NEDD8L;SKILB;USP9X;SKIB;USP9;SKIA;UCHL5
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimerUSP9;SKIB;SKILB;TRIM33;USP9X

USP9X has several biochemical functions, for example, co-SMAD binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP9X itself. We selected most functions USP9X had, and list some proteins which have the same functions with USP9X. You can find most of the proteins on our site.

Function Related Protein
co-SMAD bindingUSP9X;SMAD2;TGIF1;SMAD6;TRIM33;SMAD3;SMAD1;CITED1;GATA4
cysteine-type endopeptidase activityUSP22;PDIA3;CASP8;CASP8L1;CTSLL;FMNL3;MALT1;BLMH;CTSF
cysteine-type peptidase activityUSP43A;SENP3A;CTLA2B;ZRANB1B;CTSK;CTSSB.2;CASP6;SENP8;CTSW
protein bindingZFP335;CA4;FUT11;SH2D4A;PDE1B;USP42;ADRBK1;PML;RPL28
ubiquitin-specific protease activityUSP16;VCPIP1;TNFAIP3;USP24;FMNL3;USP7;USP43;UCHL1;USP49

USP9X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP9X here. Most of them are supplied by our site. Hope this information will be useful for your research of USP9X.

NFKB2; NUAK1; MYC; JUN; PHB; CASP4; NFKB2; RELB; MAP3K1; SMAD4; TSC22D1; NEK6; HTT

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