USP9X Protein


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Official Full Name ubiquitin specific peptidase 9, X-linked
Background This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms USP9X; ubiquitin specific peptidase 9, X-linked; FAF; FAM; DFFRX; probable ubiquitin carboxyl-terminal hydrolase FAF-X; hFAM; fat facets in mammals; ubiquitin thioesterase FAF-X; deubiquitinating enzyme FAF-X; ubiquitin thiolesterase FAF-X; fat facets protein related, X-linked; fat facets protein-related, X-linked; Drosophila fat facets related, X-linked; ubiquitin-specific protease 9, X chromosome; ubiquitin-specific processing protease FAF-X; ubiquitin-specific-processing protease FAF-X; ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila);
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Sf21 Insect Cell
    • Tag :
    • GST
    • His
    • Met
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human USP9X-184H Active Recombinant Human USP9X, GST-tagged E.coli GST
    Human USP9X-658H Active Recombinant Human USP9X, Met&His-tagged Sf21 Insect Cell Met/His
    Mouse USP9X-17945M Recombinant Mouse USP9X Protein Mammalian Cell His

    USP9X involved in several pathways and played different roles in them. We selected most pathways USP9X participated on our site, such as Downregulation of SMAD2/3:SMAD4 transcriptional activity, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP9X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Downregulation of SMAD2/3:SMAD4 transcriptional activity SKIA; RNF111; USP9; PARP1; SMAD3B; SKI; USP9X; SKILB; SKIB; TRIM33
    Gene Expression METTL3; PCBP2; AIMP1; CCDC76; LRPPRC; ZNF620; SKILB; NR2E3; CSTF1; SNRNP35
    Generic Transcription Pathway ZNF692; ZNF234; ZNF445; ZNF256; COX11; ZNF34; ZNF398; ZNF71; ZNF180; ZNF486
    Signal Transduction SOX13; FAM13A; GPR132; ANXA1C; NOG; GPR37L1; CRABP2A; PYGO1; RPE65A; PRC1
    Signaling by TGF-beta Receptor Complex CGNB; SKIA; TRIM33; UCHL5; SKILB; USP9X; USP9; USP15; SKIB; NEDD8L
    Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer SKILB; TRIM33; SKIB; USP9X; USP9

    USP9X has several biochemical functions, for example, co-SMAD binding, cysteine-type endopeptidase activity, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP9X itself. We selected most functions USP9X had, and list some proteins which have the same functions with USP9X. You can find most of the proteins on our site.

    Function Related Protein
    co-SMAD binding TGIF1; CITED1; SMAD3; TRIM33; USP9X; SMAD2; FOXH1; GATA4; SMAD1; SMAD6
    cysteine-type endopeptidase activity CTSL2; USP12; USP15; USP2; USP31; CTSJ; USP14; USP48; CTLA2B; USP40
    cysteine-type peptidase activity GM12824; CTSW; DESI1; OTUD7B; USP2A; SENP8; CTSL1; CASPA; CASP6L1; OTUD6B
    protein binding FMNL3; CCDC110; ADRBK1; UPRT; TAL2; RBL1; FAM131B; KPNB1; THRA; YWHAE
    ubiquitin-specific protease activity USP18; USP24; USP48; OTULIN; USP43A; OTUD4; USP3; MYSM1; USP47; USP2A

    USP9X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP9X here. Most of them are supplied by our site. Hope this information will be useful for your research of USP9X.


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