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Official Full Name VAV1 vav 1 guanine nucleotide exchange factor
Synonyms VAV1; vav 1 guanine nucleotide exchange factor; VAV, vav 1 oncogene; proto-oncogene vav; vav 1 oncogene; VAV;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human VAV1-163H Recombinant Human VAV1, GST-tagged Sf9 Insect Cell GST
    Human VAV1-341H Recombinant Human vav 1 guanine nucleotide exchange factor, His-tagged E.coli His
    Human VAV1-3652H Recombinant Human VAV1, His-tagged E.coli His
    Human VAV1-411H Recombinant Human VAV1 Protein, His/GST-tagged E.coli His/GST
    Human VAV1-423HCL Recombinant Human VAV1 293 Cell Lysate HEK293 N/A
    Human VAV1-6085H Recombinant Human VAV1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Vav1-412M Recombinant Mouse Vav1 Protein, His-tagged E.coli His
    Mouse Vav1-6904M Recombinant Mouse Vav1 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    vav1 involved in several pathways and played different roles in them. We selected most pathways vav1 participated on our site, such as cAMP signaling pathway, Chemokine signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with vav1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cAMP signaling pathway HTR6; PTCH1; AKT2; GRIN2C; GNAI1; GRIA1; PPP1CB; TSHR; HTR1B; ATP2B1
    Chemokine signaling pathway ROCK1; SRC; PLCB4; PLCB3; RAP1A; ADRBK2; CDC42; CXCL3; CXCL1; GNB2
    Focal adhesion VEGFC; DIAP1; DIAPH1; GSK3AA; MYL2; DOCK1; AASS; LAMA1; COL6A5; ACTN3A
    Natural killer cell mediated cytotoxicity MAPK1; HLA-A; PLCG1; IFNA1; RAF1; KIR2DS2; NCR2; Fasl; GZMB; PRKCG
    T cell receptor signaling pathway NCK1; DEF6A; CD3E; NFKBIB; GRB2; HRAS; PDCD1; PIK3R5; VAV3; GRAPA
    B cell receptor signaling pathway CARD11; GSK3AB; MAP2K1; CRK; INPPL1; PIK3R2; CD72; CD79A; DUSP6; PPP3R2
    Fc epsilon RI signaling pathway MS4A2; MAPK10; NRAS; KRAS; SYK; MAPK9; INPP5D; IL4; MAP2K4; MAP2K3
    Fc gamma R-mediated phagocytosis INPP5D; VAV1; VASP; MAP2K1; PLA2G4F; WASF1; PRKCG; PRKCE; RAC2; PLD1
    Leukocyte transendothelial migration ITGB2; ITGB1; PRKCB; PIK3CD; CDC42; PIK3CG; PIK3CA; ACTG1; PIK3CB; RAP1B
    Regulation of actin cytoskeleton PAK2; ACTB1; MYLPFA; EGFRA; PPP1R12C; TMSB4X; FGF6A; ITGA2; ACTB; PIP5K1A

    vav1 has several biochemical functions, for example, Rac guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by vav1 itself. We selected most functions vav1 had, and list some proteins which have the same functions with vav1. You can find most of the proteins on our site.

    Function Related Protein
    Rac guanyl-nucleotide exchange factor activity ARHGEF4; ARHGEF2; DOCK2; PREX2; SPATA13; FARP1; FARP2; ALS2; VAV1; VAV3
    guanyl-nucleotide exchange factor activity TIAM2; VAV3B; RAPGEF6; TBXA2R; RASGRP3; FGD1; DOCK11; TBC1D10A; DENND1C; RALGDS
    metal ion binding ZFP770; TERT; SUV39H1A; NR5A1B; PVALB6; RC3H2; MOB3A; MCM2; ARAP3; ZDHHC1
    protein binding ARF6; NFKBIZ; GIP; FAM123A; SNX15; PACS1; RARRES3; AMBP; C10orf18; CRHR2
    transcription factor activity, sequence-specific DNA binding FOSL1; CSDA; PBX1B; ZNF649; RFX1A; RFX2; ATF7; PHTF1; ZNF548; ZNF43

    vav1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with vav1 here. Most of them are supplied by our site. Hope this information will be useful for your research of vav1.

    SH3BP2; LCP2; ABL1

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