VAV1

  • Official Full Name

    VAV1 vav 1 guanine nucleotide exchange factor
  • Synonyms

    VAV1;vav 1 guanine nucleotide exchange factor;VAV, vav 1 oncogene;proto-oncogene vav;vav 1 oncogene;VAV

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Bacteria
  • Sf9 Cells
  • HEK293
  • Mammalian Cells
  • His
  • GST
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
VAV1-3652H Recombinant Human VAV1, His-tagged E.coli Human His 441-790aa
VAV1-23H Recombinant Human VAV1 Protein, Aa168-522, Y174D Mutant, N-6×His tagged Bacteria Human His 68-522
VAV1-163H Recombinant Human VAV1, GST-tagged Sf9 Cells Human GST 73-end a.a.
VAV1-341H Recombinant Human vav 1 guanine nucleotide exchange factor, His-tagged E.coli Human His 189-565 a.a.
VAV1-423HCL Recombinant Human VAV1 293 Cell Lysate HEK293 Human Non
VAV1-2334H Recombinant Human VAV1 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
VAV1-2334H-B Recombinant Human VAV1 Protein Pre-coupled Magnetic Beads HEK293 Human
VAV1-411H Recombinant Human VAV1 Protein, His/GST-tagged E.coli Human GST&His Leu426~Arg696
Vav1-412M Recombinant Mouse Vav1 Protein, His-tagged E.coli Mouse His Gly565~Ala795
VAV1-6085H Recombinant Human VAV1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
VAV1-6547H Recombinant Human VAV1 Protein (Leu426-Arg696), N-GST tagged E.coli Human GST Leu426-Arg696
Vav1-6904M Recombinant Mouse Vav1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
VAV1-919HFL Recombinant Full Length Human VAV1 Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.

    Involved Pathway

    VAV1 involved in several pathways and played different roles in them. We selected most pathways VAV1 participated on our site, such as cAMP signaling pathway,Chemokine signaling pathway,Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAV1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    T cell receptor signaling pathway NFATC1,SOS1,PDPK1,PIK3CD,GRAPA,NFATC3,CBLC,PIK3R2,AKT1,PAK7
    Fc gamma R-mediated phagocytosis ARF6,PRKCD,PIK3CG,RAC2,PIP5K1A,PIK3R2,PTPRC,PLD2,GAB2,PIK3CD
    cAMP signaling pathway MAPK8,PLD1,RRAS2,CNGA2,TNNI3,GRIN2A,ATP1A3,PIK3CB,GRIN2B,CNGA4
    Fc epsilon RI signaling pathway PDPK1,IL13,MAPK1,GM-CSF,PLA2G4C,GAB2,KRAS,NRAS,AKT1,PIK3R2
    Focal adhesion THBS4A,Itga10&Itgb1,COL5A1,PDGFA,THBS2,PAK2A,PIK3CA,DIAP1,LAMC1,SHC3
    Chemokine signaling pathway RAC1,GRB2,CCL4,CRKL,GNB3,CXCR6,PLCB3,CCL3L3,CCL8,PRKACB
    Leukocyte transendothelial migration NCF4,CTNNA3,CLDN15,ICAM1,CD99,BCAR1,CLDN14,NOX3,ROCK1,MYLPF
    Regulation of Actin Cytoskeleton MYLK4,PDGFD,PIK3R2,PFN1,WASB,MYL12.2,F2R,PIKFYVE,INSB,FGF20
    B Cell Receptor Signaling Pathway KRAS,ACTR3,LYN,LAT2,PRKCB,PIK3R1,CD22,RAC3,PIK3CG,ARPC1B

    Protein Function

    VAV1 has several biochemical functions, for example, Rac guanyl-nucleotide exchange factor activity,guanyl-nucleotide exchange factor activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VAV1 itself. We selected most functions VAV1 had, and list some proteins which have the same functions with VAV1. You can find most of the proteins on our site.

    Function Related Protein
    transcription factor activity, sequence-specific DNA binding FOXN3,STAT3,ZNF167,HDAC1,ZNF498,PAX3,HOXA5,DMRT3,ZNF726,ZNF649
    metal ion binding HENMT1,REV1,HMGCL,ACVR2B,ZFP91,NCALDA,RHOT1A,PVALB3,CSH1,NAALAD2
    Rac guanyl-nucleotide exchange factor activity FARP2,ARHGEF2,VAV3,PREX2,DOCK2,FARP1,ALS2,ARHGEF4,SPATA13
    guanyl-nucleotide exchange factor activity RASGRP2,ARHGEF3L,RASGRF2B,FGD2,FFAR1,ARHGEF7A,RAPGEF6,GCGR,P2RY12,CHRM4
    protein binding GLRX3,CEP170L,TESC,OTUB2,PTRH2,SLU7,HCST,ELOVL6,MRC1,RC3H2

    Interacting Protein

    VAV1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAV1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VAV1.

    SH3BP2;LCP2;ABL1

    VAV1 Related Signal Pathway

    Resources

    References

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