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  • Official Full Name

    VAV1 vav 1 guanine nucleotide exchange factor

  • Synonyms

    VAV1; vav 1 guanine nucleotide exchange factor; VAV, vav 1 oncogene; proto-oncogene vav; vav 1 oncogene; VAV;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Bacterial expression system
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian cells
  • Sf9 Insect Cell
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
  • 6×His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VAV1-23H Recombinant Human VAV1 Protein, Aa168-522, Y174D Mutant, N-6×His tagged Bacterial expression system N-6×His 68-522
Human VAV1-341H Recombinant Human vav 1 guanine nucleotide exchange factor, His-tagged E.coli His
Human VAV1-3652H Recombinant Human VAV1, His-tagged E.coli His 441-790aa
Human VAV1-163H Recombinant Human VAV1, GST-tagged Sf9 Insect Cell GST
Human VAV1-423HCL Recombinant Human VAV1 293 Cell Lysate HEK293 N/A
Human VAV1-411H Recombinant Human VAV1 Protein, His/GST-tagged E.coli His/GST Leu426~Arg696
Human VAV1-6085H Recombinant Human VAV1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human VAV1-919HFL Recombinant Full Length Human VAV1 Protein, C-Flag-tagged Mammalian cells Flag
Human VAV1-2334H Recombinant Human VAV1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human VAV1-2334H-B Recombinant Human VAV1 Protein Pre-coupled Magnetic Beads HEK293
Human VAV1-6547H Recombinant Human VAV1 Protein (Leu426-Arg696), N-GST tagged E.coli N-GST Leu426-Arg696
Mouse Vav1-6904M Recombinant Mouse Vav1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Vav1-412M Recombinant Mouse Vav1 Protein, His-tagged E.coli His Gly565~Ala795
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • VAV1 Related Signal Pathway

VAV1 involved in several pathways and played different roles in them. We selected most pathways VAV1 participated on our site, such as cAMP signaling pathway, Chemokine signaling pathway, Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with VAV1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cAMP signaling pathwayCAMK2A;NPY;PAK1;RRAS;ATP1B4;PDE4D;ATP1B3;GHRL;EP300
Chemokine signaling pathwayCCL5;PIK3R5;NRAS;CCL8;PRKCB;CCL4;CXCR1;CXCR5;SHC1
Natural killer cell mediated cytotoxicityRAET1E;IFNA14;ARAF;KLRD1;IFNA5;IFNA8;HLA-G;KIR2DS5;LCP2
T cell receptor signaling pathwayDBNLB;PAK6;CARD11;MAP2K7;PAK3;VAV2;DLG1;MAPK12;CBL
B cell receptor signaling pathwayNFATC2;PIK3CB;MAPK3;LYN;NFKBIA;MAP2K2;GSK3AB;IKBKG;INPPL1
Fc epsilon RI signaling pathwayIL3;INPP5D;MAPK3;PLA2G4D;RAC2;TNF;FCER1G;VAV1;SOS1
Fc gamma R-mediated phagocytosisPLA2G4F;PIK3CB;AMPH;CDC42;GSN;MAPK3;PIP5K1A;WASF1;PIK3R5
Leukocyte transendothelial migrationRAC1;Itgam&Itgb2;CLDN4;PTK2B;VCAM1;PTPN11;ESAM;ACTN4;PECAM1
Regulation of actin cytoskeletonMYH9;Itga10&Itgb1;EGFRA;PDGFA;CFL2L;RDX;PFN3;MYLK4;ITGA5

VAV1 has several biochemical functions, for example, Rac guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VAV1 itself. We selected most functions VAV1 had, and list some proteins which have the same functions with VAV1. You can find most of the proteins on our site.

Function Related Protein
Rac guanyl-nucleotide exchange factor activityDOCK2;ALS2;PREX2;VAV1;VAV3;SPATA13;FARP1;ARHGEF2;FARP2
guanyl-nucleotide exchange factor activityKNDC1;EIF2B5;ARHGEF4;RALGPS1;RAPGEF4;RIC8B;FGD6;RPGR;VAV2
metal ion bindingSTK32C;SOD3A;ZFP13;NME2;GALNT10;HNRNPA0L;OMA1;LMAN2;PRDM15
protein bindingMETTL17;DHPS;TIGIT;AGPS;Abcb1b;GPR85;ZNF230;ALS2;RPS27L
transcription factor activity, sequence-specific DNA bindingFOXD2;NFIA;CDX1B;AATF;ZHX1;CBFA2T3;NR6A1A;NPAS1;POU3F2A

VAV1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VAV1 here. Most of them are supplied by our site. Hope this information will be useful for your research of VAV1.


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