wtap Protein, Wilms tumor 1 associated protein


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Official Full Name Wilms tumor 1 associated protein
Background The Wilms tumor suppressor gene WT1 appears to play a role in both transcriptional and posttranscriptional regulation of certain cellular genes. This gene encodes a WT1-associating protein, which is a ubiquitously expressed nuclear protein. Like WT1 protein, this protein is localized throughout the nucleoplasm as well as in speckles and partially colocalizes with splicing factors. Alternative splicing of this gene results in three transcript variants, two of which encode the same isoform.
Synonyms WTAP; Wilms tumor 1 associated protein; pre-mRNA-splicing regulator WTAP; KIAA0105; MGC3925; hFL(2)D; PNAS-132; WT1-associated protein; female-lethal(2)D homolog; wilms tumor 1-associating protein; Wilms tumour 1-associating protein; putative pre-mRNA spl
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human WTAP-186H Recombinant Human WTAP protein, T7-tagged E.coli T7
    Human WTAP-276HCL Recombinant Human WTAP 293 Cell Lysate HEK293 N/A
    Human WTAP-277HCL Recombinant Human WTAP 293 Cell Lysate HEK293 N/A
    Human WTAP-3014H Recombinant Human Wilms Tumor 1 Associated Protein, T7-tagged E.coli T7
    Human WTAP-31529TH Recombinant Human WTAP, T7 -tagged E.coli T7
    Human WTAP-321H Recombinant Human WTAP protein, GST-tagged Insect Cell GST
    Human WTAP-3744H Recombinant Human WTAP, GST-tagged E.coli GST
    Human WTAP-447H Recombinant Human WTAP Protein, His-tagged E.coli His
    Human WTAP-7047H Recombinant Human WTAP, GST tagged E.coli GST
    Mouse WTAP-18591M Recombinant Mouse WTAP Protein Mammalian Cell His
    Rhesus Macaque WTAP-5223R Recombinant Rhesus monkey WTAP Protein, His-tagged Mammalian Cell His
    Zebrafish WTAP-10226Z Recombinant Zebrafish WTAP Mammalian Cell His

    wtap involved in several pathways and played different roles in them. We selected most pathways wtap participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with wtap were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression TRMT5; POU2F1; CD2BP2; AGO3B; ZNF701; ZNF45; ZFP2; PRDX2; ZNF436; ZNF563
    Processing of Capped Intron-Containing Pre-mRNA DNAJC8; HNRNPL; HNRNPUL1; SF3A1; PTBP1; NUDT21; WTAP; THOC4; SLBP; CD2BP2

    wtap has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by wtap itself. We selected most functions wtap had, and list some proteins which have the same functions with wtap. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TCEB1; CCND1; RBM4; DHX15; USP54; NUP50; CREBZF; MYB; LAMTOR2; MTMR4

    wtap has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with wtap here. Most of them are supplied by our site. Hope this information will be useful for your research of wtap.

    IKZF1; VPS52; YWHAZ; MAGEA11; TAB1; Sod1; Srsf1; METTL3

    Venkatareddy, M; Wang, S; et al. Estimating Podocyte Number and Density Using a Single Histologic Section. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 25:1118-1129(2014).
    Leader, R; Deol-Poonia, RK; et al. Immunohistochemical localization of WT1 in epithelial salivary tumors. PATHOLOGY RESEARCH AND PRACTICE 210:726-732(2014).

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