Creative BioMart has developed a novel approach to both increase biological activities and reduce production costs of human synthetic proteins in mammalian cell lines. The stable transfection of particular cell lines with human sialyltransferases (a set of enzymes involves in protein glycosylation) has largely enhanced bioavailability and activity of synthetic human proteins which are critical properties for the therapeutic application. Besides, proteins produced by this technology display glycosylation patterns similar to those obtained in human cells.
This glycosylation pattern increases humanization of proteins and has the following advantages :
Examples of successful applications:
Creative BioMart has decades of experiences in cell line development to manufacture proteins and has established various platforms to provide high quality product. If you are interested, welcome to contact us for detailed information.
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