Active Recombinant Mouse Kdr Protein, Fc/His-tagged, Alexa Fluor 647 conjugated

• Cat.No.: Kdr-1786MAF647
• Product Overview: Alexa Fluor 647 conjugated recombinant mouse VEGFR2 encoding amino acid residues 1-762 of the extracellular domain was fused to the 6X his-tagged Fc of human IgG1 via the peptide (IEGRMD). The chimeric protein was expressed in NSO cells.

Specification

• Description: Vascular endothelial growth factor receptor 2 (VEGF R2) is a transmembrane glycoprotein that is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration, and differentiation.
• Source: Mammalian cells
• Species: Mouse
• Tag: Fc/His
• Form: Lyophilized
• Bio-activity: The biological activity of Mouse VEGFR2 was determined by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells. The expected ED50 for this effect is typically 10-30 ng/mL in the presence of 5 ng/mL of rmVEGF.
• Molecular Mass: 166-191 kDa
• Endotoxin: < 1.0 EU/ μg as determined by the LAL method
• Purity: > 90 % by SDS-PAGE and analyzed by silver stain
• Characteristic: Disulfide-linked homodimer
  Labeled with Alexa Fluor 647 via amines
  Excitation = 650 nm
  Emission = 668 nm
• Stability: This lyophilized protein is stable for 6 to 12 months when stored desiccated at -20 to -70 centigrade. After aseptic reconstitution, this protein may be stored at 2 to 8 centigrade for one month or at -20 to -70 centigrade in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20 to -70 centigrade. After aseptic reconstitution, this protein may be stored at 2 to 8 centigrade for one month or at -20 to -70 centigrade in a manual defrost freezer.
• Storage Buffer: This recombinant protein was 0.2 μm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1 × PBS) pH 7.2-7.3 with no calcium, magnesium, or preservatives.

Gene Information

• Gene Name: Kdr kinase insert domain protein receptor [ Mus musculus ]
• Official Symbol: Kdr
• Synonyms: Kdr; kinase insert domain protein receptor; Flk1; Ly73; Flk-1; Krd-1; VEGFR2; VEGFR-2; sVEGFR-2; 6130401C07; VEGF receptor-2; OTTMUSP00000023578; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; vascular endothelial growth factor receptor- 2; soluble vascular endothelial growth factor receptor 2; EC 2.7.10.1
• Gene ID: 16542
• mRNA Refseq: NM_010612
• Protein Refseq: NP_034742
• UniProt ID: P35918