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Recombinant Human MAP/Microtubule Affinity-Regulating Kinase 3, GST-His-tagged

Cat.No. : MARK3-5450H
Product Overview : Recombinant humanfull length MARK3 (amino acids M1-L713) N-terminally fused to GST-His6-Thrombincleavage site.
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  • Gene Information
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Cat. No. : MARK3-5450H
Description : MARK3 encoded bythis gene is activated by phosphorylation and in turn is involved in thephosphorylation of tau proteins MAP2 and MAP4. Several transcript variantsencoding different isoforms have been found for this gene.
Source : Sf9 insect cells
Species : Human
Form : Liquid in 50 mMHEPES, pH 7.5 + 100 mM NaCl + 5 mM DTT + 4 mM reduced glutathione + 20%glycerol
Molecular Weight : 109.4 kDa
Concentration : 0.082 mg/ml
Purity : Affinity purifiedusing GSH-agarose
Specific Activity : 18 pmol/µg x min. Assaybuffer: 60 mM HEPES-NaOH, pH 7.5 + 3 mM MgCl2 + 3 mM MnCl2 + 3 µMNa-orthovanadate + 1.2 mM DTT + 2.5 µg/50 µl PEG20.000 + ATP (variable) +0.25 µg/50 µl CHKtide substrate + 200 ng/50 µl MARK3.
Storage : Store in workingaliquots at -80°C. Avoid repeated freeze-thaw cycles.
OfficialSymbol : MARK3
Gene Name : MARK3 MAP/microtubuleaffinity-regulating kinase 3 [ Homo sapiens ]
Synonyms : MARK3;MAP/microtubule affinity-regulating kinase 3; KP78; CTAK1; PAR1A; Par-1a;EMK-2; C-TAK1; OTTHUMP00000246863; OTTHUMP00000246864; OTTHUMP00000246865;OTTHUMP00000246866; OTTHUMP00000246867; OTTHUMP00000246868; ELKL motif kinase2; protein kinase STK10; ser/Thr protein kinase PAR-1; cdc25C-associatedprotein kinase 1; rine/threonine-protein kinase p78; EC 2.7.11.1
Gene ID : 4140
mRNA Refseq : NM_002376
Protein Refseq : NP_002367
MIM : 602678
UniProt ID : P27448
Chromosome Location : 14q32.3
Function : ATP binding;nucleotide binding; protein binding; protein serine/threonine kinaseactivity; transferase activity, transferring phosphorus-containing groups

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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