Recombinant Human EPHA8, GST-tagged

• Cat.No.: EPHA8-6999H
• Product Overview: Recombinant human EPHA8 (565-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: EPHA8 is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family in ahich EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. EPHA8 receptors play a role in axonal pathfinding during development of the mammalian nervous system.
• Source: Sf9 Cells
• Species: Human
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~82 kDa
• Protein length: 565 aa-end
• Purity: >90%
• Applications: Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1 μg/μl

Gene Information

• Gene Name: EPHA8 EPH receptor A8 [ Homo sapiens ]
• Official Symbol: EPHA8
• Synonyms: EPHA8; EPH receptor A8; EEK, EphA8; ephrin type-A receptor 8; Hek3; EPH-like kinase 3; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; tyrosine-protein kinase receptor EEK; EEK; EK3; HEK3; KIAA1459
• Gene ID: 2046
• mRNA Refseq: NM_001006943
• Protein Refseq: NP_001006944
• MIM: 176945
• UniProt ID: P29322
• Chromosome Location: 1p36.12
• Pathway: Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; EPHA forward signaling, organism-specific biosystem; EphrinA-EPHA pathway, organism-specific biosystem
• Function: ATP binding; GPI-linked ephrin receptor activity; nucleotide binding; receptor activity