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Recombinant Human GPA33 protein, His-tagged

Cat.No. : GPA33-244H
Product Overview : Recombinant Human GPA33 (Ile22-Val235) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).
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Description : Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.
Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Ile22
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 24.5 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Ile22-Val235
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >96% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : GPA33
Official Symbol : GPA33
Synonyms : GPA33; glycoprotein A33 (transmembrane); cell surface A33 antigen; A33; transmembrane glycoprotein A33; MGC129986; MGC129987
Gene ID : 10223
mRNA Refseq : NM_005814
Protein Refseq : NP_005805
MIM : 602171
UniProt ID : Q99795

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Are there any known diseases associated with GPA33? 09/25/2022

Colorectal cancer is associated with abnormal expression of GPA33.

Is GPA33 membrane-bound? 09/25/2021

Yes, GPA33 is a membrane-associated protein.

What role does GPA33 play in cancer? 08/25/2021

GPA33 is implicated in colorectal cancer and is used as a marker for cancer diagnosis.

Is there a known molecular function for GPA33? 05/09/2021

The provided information doesn't specify a detailed molecular function for GPA33.

What is the significance of GPA33 in cell adhesion? 05/29/2020

GPA33's role in cell adhesion suggests it may have implications in cellular interactions and tissue organization.

What is the function of GPA33? 02/22/2020

GPA33 is a cell surface protein involved in cell adhesion and is associated with colorectal cancer.

Is GPA33 widely expressed in tissues? 05/17/2019

The provided information doesn't specify the tissue expression pattern of GPA33.

Customer Reviews (3)

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Reviews
12/03/2022

    We valued the product's safety profile, which ensured the well-being of our researchers and the integrity of our experiments.

    06/05/2019

      The product's biocompatibility with various cell types and organisms made it versatile for a wide range of applications.

      08/27/2018

        The product's unique attributes propelled our research to innovative heights.

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