Recombinant Human TAO Kinase 1, GST-tagged, Active

• Cat.No.: TAOK1-441H
• Product Overview: Recombinant human TAOK1 (1-314) was expressed by baculovirus inSf9insect cells using an N-terminal GST tag. MW = 63 kDa.

Specification

• Cat. No.: TAOK1-441H
• Description: TAOK1 is a serine/threonine-protein kinase involved in regulation of the p38-containing stress-responsive MAP kinase pathway and extracellular signal-regulated protein kinase (ERK) kinases (MEKs). The activation of and binding to MEK3 by TAOK1 implicates TAOK1 in the regulation of the p38-containing stress-responsive MAP kinase pathway. A microtubule affinity-regulating kinase kinase, TAOK1 (also known as MARKK) is an important regulator of mitotic progression, required for both chromosome congression and checkpoint-induced anaphase delay.
• Source: Sf9 insect cells using baculovirus.
• Sequence: 1-314.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: TAOK1 TAO kinase 1 [ Homo sapiens ]
• Synonyms: TAOK1; TAO kinase 1; PSK2; TAO1; MARKK; MAP3K16; FLJ14314; KIAA1361; STE20-like kinase; serine/threonine kinase TAO1; serine/threonine protein kinase TAO1 homolog; microtubule affinity regulating kinase kinase; EC 2.7.11.1; hKFC-B; Kinase from chicken homolog B; STE20-like kinase PSK2; Thousand and one amino acid protein 1; Serine/threonine-protein kinase TAO1
• Gene ID: 57551
• mRNA Refseq: NM_020791
• Protein Refseq: NP_065842
• MIM: 610266
• UniProt ID: Q7L7X3
• Chromosome Location: 17q11.2
• Pathway: MAPK signaling pathway
• Function: ATP binding; nucleotide binding; protein kinase activator activity; protein kinase binding; protein serine/threonine kinase activity; transferase activity